Results 221 to 230 of about 449,850 (290)

Substrate-Selective Lipolysis Facilitates Unsaturated TAG Accumulation in Obesity. [PDF]

Diabetes
Sheng J, Qi S, Chan M, Wang E, Han X, Hsueh WA, Yang L, Wong STC.   +7 more
europepmc   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Effect of Passive Prechamber and Direct Water Injection on Performance and Efficiency Improvement within a Gasoline Engine. [PDF]

ACS Omega
Wei W, Liu Q, Feng S, Li L, Lv Y, Kang Z.   +5 more
europepmc   +1 more source

Single-cell landscape of human adipose tissue reveals THBS1 as a potential driver of fibro-inflammation in metabolic disease. [PDF]

Nat Commun
Jung J, Park ES, Lee NK, Lee JJ, Juang U, Huang Q, Park YS, Kim HJ, Kim JK, Oh TJ, Suh JM, Kim JB, Moon JH, Kim JK, Choi SH.   +14 more
europepmc   +1 more source

The Media Bias Detector: A framework for annotating and analyzing the news. [PDF]

Sci Adv
Haider S, Tohidi A, Wang JS, Dörr T, Rothschild DM, Callison-Burch C, Watts DJ.   +6 more
europepmc   +1 more source

Synergistic Regulation of Deep-Cycling-Induced Zn Pulverization and Resting Galvanic Corrosion in Practical Lean Zinc Anodes. [PDF]

Adv Sci (Weinh)
Xu J, Li H, Jing Q, Zhao L, Ballas E, Sun B, Aurbach D, Wang G.   +7 more
europepmc   +1 more source

Body Composition Phenotypes and Their Metabolic Associations in Treatment-Naïve Patients With Newly Diagnosed Type 2 Diabetes: A DXA-Based Cluster Analysis. [PDF]

Endocrinol Diabetes Metab
Zhang X, Zhang R, Jiang T.
europepmc   +1 more source