Results 261 to 270 of about 1,156,542 (355)

Pharmacologic Treatments for the Preservation of Lean Body Mass During Weight Loss. [PDF]

J Clin Med
Arora G, Conde KR, Desouza CV.
europepmc   +1 more source

Lean-ing on Quality: How High-Quality Data Beats Diverse Multilingual Data in AutoFormalization [PDF]

W.-Y. Chan, Michael Souliman, Jakob Nordhagen, Brando Miranda, Elyas Obbad, Kai Fronsdal Sanmi Koyejo   +5 more
openalex   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Muscle Loss in Obesity Therapy as a Therapeutic Target: Trial Design and Endpoints for Regulatory Discussions. [PDF]

J Cachexia Sarcopenia Muscle
von Haehling S, Sato R, Langer H, Khan MS, Coats AJS, Evans W, Heymsfield S, Anker SD.   +7 more
europepmc   +1 more source

Habituation to the pleasure elicited by sweetness in lean and obese women

, 2012
Marta Yanina Pepino, Julie A. Mennella
openalex   +2 more sources

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

The Benefits of Exercise Training in Combination With Weight Loss Therapies. [PDF]

Diabetes
Jiang BC, Villareal DT.
europepmc   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Neonatal hyperoxia exposure does not exacerbate hypertension programmed by maternal obesity. [PDF]

Am J Physiol Regul Integr Comp Physiol
do Carmo JM, Hall JE, Dai X, Ladnier E, Wang Z, Mouton AJ, da Silva AA.   +6 more
europepmc   +1 more source