Results 61 to 70 of about 1,126,251 (289)

Lean Construction: IGLC research evolution and agenda for the future [PDF]

, 2021
The way Lean Construction has evolved within the construction industry is still not entirely clear. Inspired by lean manufacturing, there are differences in the output of the construction industry, thus resulting in differences between both types of ...
Mano, Aline Patricia, Lima, Edson Pinheiro de, da Costa, Sergio E. Gouvea, Jacob, Francois   +3 more
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Transplantation of an obesity-associated human gut microbiota to mice induces vascular dysfunction and glucose intolerance

Gut Microbes, 2021
Recent preclinical data suggest that alterations in the gut microbiota may be an important factor linking obesity to vascular dysfunction, an early sign of cardiovascular disease.
S. Raj J. Trikha, Dustin M. Lee, Kayl E. Ecton, Scott D. Wrigley, Allegra R. Vazquez, Nicole S. Litwin, Keely N. Thomas, Yuren Wei, Micah L. Battson, Sarah A. Johnson, Kristine A. Kuhn, Sean P. Colgan, Christopher L. Gentile, Tiffany L. Weir   +13 more
doaj   +1 more source

Lean Accounting Comes to Lean Software Development [PDF]

SSRN Electronic Journal, 2017
I argue that lean software development firms become more productive if they align their lean managerial accounting systems and lean software development processes. I conduct an experiment on software development teams that have used lean and agile software development practices.
openaire   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Lean accounting [PDF]

, 2018
Työn tarkoituksena on tutkia kuinka Lean accounting vaikuttaa yrityksen Lean-toimintaan ja mikä on sen soveltamisesta koettu hyöty. Perehdyn aiheessani Lean-ajatteluun, keskeisiin käsitteisiin, Lean accounting eroihin perinteiseen laskentatoimeen ...
Sand, Fanni
core  

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Lean accounting tools and competitive advantage in Jordanian industrial companies

Cogent Business & Management
This study explores the impact of lean accounting tools—specifically value stream costing (VSC), target costing (TC), and kaizen costing (KCO)—on the competitive advantage (CA) of industrial companies in Jordan.
Ayman Mohammad ALShanti, Khalil Mahmoud Ali Al-Refae, Mohammad Jebreel   +2 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Análisis de inversión y reducción de costos en un contexto de Lean Accounting

Contabilidad y Negocios: Revista del Departamento Académico de Ciencias Administrativas, 2023
En la presente investigación, se desarrolla y explica paso a paso cómo identificar el ahorro de costos en una empresa que usa lean accounting, y cómo esos ahorros se integran para evaluar un proyecto de inversión.
Jerónimo Alberto Colazo, Marcela Porporato   +1 more
doaj