Results 131 to 140 of about 40,859 (264)

Underlying MASLD-induced gut microbiome dysbiosis and intestinal inflammation are key to poor outcomes in vibriosis infections in a preclinical model. [PDF]

Gut Microbes
Saha P, Roy S, More M, Bose D, Trivedi A, Brooks BW, Syn WK, Diehl AM, Chatterjee S.   +8 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Effect of Supplementation with Red Rooibos Tea on Body Composition, Metabolic Outcomes, and Movement in Ovariectomized Sprague-Dawley Rats. [PDF]

Curr Dev Nutr
Feld RS, Ianiero MA, Goncharow MK, Kays DB, Madanat S, MacPherson RE, Roy BD, Ward WE.   +7 more
europepmc   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

FEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

Quantifying Anterior Cruciate Ligament Injury Resilience: A Screening and Composite Score Framework. [PDF]

Orthop J Sports Med
Seagers K, Swaminathan K, Kolesar J, Hamner S, Muccini J, Hicks J, Myer G, Hastie T, Delp S.   +8 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Dynamics of in-hospital body composition changes in mild and moderately severe acute pancreatitis: trajectories and predictors. [PDF]

Front Nutr
Sun D, Zhou X, Li H, Lin H.
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Substantial aircraft contrail formation at low soot emission levels. [PDF]

Nature
Voigt C, Märkl R, Sauer D, Dischl R, Renard C, Seeliger K, Yu F, Kaufmann S, Bräuer T, Jurkat-Witschas T, Le Chenadec G, Moreau J, Requena-Esteban E, Bonne N, Vals M, Roche A, Zelina J, Dörnbrack A, Eirenschmalz L, Heckl C, Horst E, Lichtenstern M, Marsing A, Neumann G, Roiger A, Scheibe M, Stock P, Giez A, Eckel G, Le Clercq P.   +29 more
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source