Results 51 to 60 of about 114,173 (308)

Association between Sleep Quality and Body Composition in Sedentary Middle-Aged Adults

Medicina, 2018
Background: Ageing is associated with sleep pattern changes and body composition changes, which are related to several diseases. Purpose: This study aimed to analyse the association between sleep quality and an extensive set of body composition ...
Lucas Jurado-Fasoli, Francisco J. Amaro-Gahete, Alejandro De-la-O, Manuel Dote-Montero, Ángel Gutiérrez, Manuel J. Castillo   +5 more
doaj   +1 more source

The Relationship of Lean Body Mass With Aging to the Development of Diabetes [PDF]

Journal of the Endocrine Society, 2020
Abstract Context Older adults have the greatest burden of diabetes; however, the contribution of age-related muscle loss to its development remains unclear. Objective We assessed the relationship of lean body mass with aging to ...
Rita R. Kalyani, Stephanie A. Studenski, Mohammed E. Al-Sofiani, Mohammed E. Al-Sofiani, Nancy Chiles Shaffer, Hermes Florez, Chee W. Chia, Josephine M. Egan, Luigi Ferrucci, E. Jeffrey Metter, Sherita Hill Golden, Qian Li Xue   +11 more
openaire   +3 more sources

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Circulating Metabolites Associated with Body Fat and Lean Mass in Adults with Overweight/Obesity

Metabolites, 2021
The interplay between fat mass and lean mass within human metabolism is not completely understood. We aimed to identify specific circulating metabolomic profiles associated with these body composition compartments. Cross-sectional analyses were conducted
Christopher Papandreou, Jesús García-Gavilán, Lucía Camacho-Barcia, Thea T. Hansen, Anders Sjödin, Joanne A. Harrold, Jason C. G. Halford, Mònica Bulló   +7 more
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Body composition in professional female netball players within and between seasons: a cohort study

BMC Sports Science, Medicine and Rehabilitation, 2021
Background There is limited information on the physique attributes of female netball players from the highest playing standards and the typical body composition changes that occur with training and competition in these athletes. The purpose of this study
Luke Hogarth, Ava Farley, Max McKenzie, Brendan Burkett, Mark McKean   +4 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Arterial health during early childhood following abnormal fetal growth

BMC Pediatrics, 2022
Background Abnormal fetal growth is associated with increased cardiovascular risk in adulthood. We investigated the effect of fetal programming on arterial health and morphology during early childhood.
Rasmus F.W. Olander, Johnny K.M. Sundholm, Sanna Suonsyrjä, Taisto Sarkola   +3 more
doaj   +1 more source

Teaching Python with team‐based learning: using cloud‐based notebooks for interactive coding education

FEBS Open Bio, EarlyView.
This study presents a novel approach to teaching Python and bioinformatics using team‐based learning and cloud‐hosted notebooks. By integrating interactive coding into biomedical education, the method improves accessibility, student engagement, and confidence—especially for those without a computing background.
Nuno S. Osório, Leonardo D. Garma
wiley   +1 more source

Body fat mass and lean mass as predictors of survival in hemodialysis patients [PDF]

Kidney International, 2006
A higher body mass index (BMI) is a predictor of better survival in hemodialysis patients, although the relative importance of body fat and lean mass has not been examined in the dialysis population. We performed an observational cohort study in 808 patients with end-stage renal disease on maintenance hemodialysis. At baseline, fat mass was measured by
Sawako Hatsuda, Eiji Ishimura, Hidenori Koyama, Noriyuki Tatsumi, Y. Nishizawa, Takuhito Shoji, Eiji Kimoto, Tsutomu Tabata, M. Emoto, Takami Miki, Hideki Tahara, Kayo Shinohara, Ryusuke Kakiya, Yoshihiro Tsujimoto   +13 more
openaire   +3 more sources