Results 41 to 50 of about 319,318 (302)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
An exploration of knowledge and understanding – the eighth flow [PDF]
, 2013 The argument for understanding Lean construction as a socio-technical field is growing and the need to better consider the role of human beings within construction systems is becoming the dominant factor in project success.
Court, P, Pasquire, C
core
How BIM-lean integration enhances the information management process in the construction design [PDF]
, 2017 The construction industry faces significant challenges due to insufficient processes. Design phase is a key process of construction project lifecycle in which many problems and challenges occur. Most of the issues within the design process are mainly due
Abou Moemen, AA +6 more
core +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
AN INVESTIGATION INTO THE USAGE OF LEAN CONSTRUCTION TECHNIQUES IN NIGERIA
Journal of Construction Project Management and Innovation, 2017 Inadequate implementation of lean construction techniques poses a serious problem to the Nigerian construction process. The usage of lean techniques at the early stage of construction projects results in enhanced environmental performance, waste ...
Olatunji J OLADIRAN
doaj +1 more source
Suggestions to Improve Lean Construction Planning [PDF]
, 2015 The Last Planner System® has been one of the most popular lean construction tools that offers a solution to tackle the problems of production management on construction sites.
Dave, Bhargav +4 more
core
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Moving on - beyond lean thinking [PDF]
, 2004 Lean Thinking is currently often positioned as the underlying theory of lean production among practitioners and academics, although its originators, Womack and Jones, seem not to have presented it as a theory.
Koskela, LJ
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source