Results 61 to 70 of about 528,943 (339)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Enabling initiation of a lean management system in SMEs: a case study of a high performance plastics manufacturer [PDF]

open access: yes, 2013
This paper investigates the challenges in developing a Lean Management System in a typical Small to Medium Size Enterprise (SME’s) in the UK. Through a series of pilot projects measured and implemented by action research this case study reflects on the ...
Jalali-Roudsari, Mehdi, Murray, Susan
core  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Adoption of Lean Management Principles in Small, Medium-Sized and Large Manufacturing Enterprises

open access: yesKvalita Inovácia Prosperita
Purpose: The paper aims to determine the adoption of lean management principles in the manufacturing industry, focusing on SMEs and analysing whether there are differences between enterprises according to their size. Methodology/Approach: The research
Martin Pech, Eva Jelínková
doaj   +1 more source

Implementation of Lean management Practices in Azerbaijan (on the Example of a Private Company)

open access: yesInternational Journal of Engineering and Management Sciences, 2023
Organizations are facing crucial modifications as global market and conditions change day after day. To keep up with fast changing realities, it’s important to apply innovation decisions to the current stage of organizations.
Yelena Alaskarova   +2 more
doaj   +1 more source

Measuring the level of lean readiness of the Hong Kong's manufacturing industry [PDF]

open access: yes, 2016
Increasingly competitive business environments have forced manufacturing organisations to continuously seek improvements in their production processes as an alternative to achieve operational excellence. Lean manufacturing principles and techniques based
Garza-Reyes, Jose Arturo   +3 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Management in the Portsmouth Block Mill, 1803-1812 [PDF]

open access: yes, 2015
The Portsmouth Block Mills’ operations are assessed using archival materials showing staff numbers, hours and work assignments, providing insight into scheduling and workload management, capacity availability and use, and overall facility organization ...
Wilson, James M.
core   +1 more source

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