Results 151 to 160 of about 221,276 (349)

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Impact Of Lean Manufacturing Practices On Job Satisfaction Among Employees In Lean Manufacturing Companies; Moderated By Lean Culture And Mediated By Job Characteristics [PDF]

, 2012
Objektif kajian ini adalah untuk menyiasat kesan amalan pembuatan lean terhadap kepuasan kerja di kalangan kakitangan syarikat-syarikat pembuatan lean, ditapis oleh budaya lean dan berperantaraan dengan ciri kerja.
Khaw, Sui Minh
core  

Analisis Waste Pada Proses Produksi Sosis Ayam Dengan Pendekatan Lean Manufacturing Di PT. BI

, 2023
Giari Ayunintya Pratiwi, Asep Erik Nugraha   +1 more
openalex   +2 more sources

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

The role of a manufacturing execution system during a lean improvement project [PDF]

, 2011
Observation is a key aspect within a Lean improvement project. The project team starts from scratch and analyses the current situation by walking through the production process. During the last decade, the digitization of manufacturing operations has had
Cottyn, Johannes, Derammelaere, Stijn, Stockman, Kurt, Van Landeghem, Hendrik   +3 more
core   +1 more source

O impacto do lean manufacturing como fator de melhoria no desempenho produtivo

, 2018
Leoni Pentiado Godoy, Nara Medianeira Stefano, Wagner Pietrobelli Bueno, Taís Pentiado Godoy, Roger da Silva Wegner   +4 more
openalex   +2 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

A Hands-On, Active Learning Approach to Increasing Manufacturing Knowledge in Engineering Students [PDF]

, 2013
This paper describes a new learning module implemented as part of the senior capstone design course at Marquette University to teach engineering students about basic manufacturing processes, lean manufacturing principles, and design for manufacturability.
Goldberg, Jay R., Rank, David B.
core   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Integrating Lean Principles into Lean Robotics Systems for Enhanced Production Processes

Systems
Integrating lean principles into lean robotics systems emerges as a transformative path for production processes. This paper addresses the question of what are the best practices of integrating lean principles within robotics systems to enhance ...
Stelian Brad, Eyas Deeb
doaj   +1 more source