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The authors reply: Letter on: “Pitfalls in the measurement of muscle mass: a need for a reference standard” by Clark et al.

open access: yesJournal of Cachexia, Sarcopenia and Muscle, 2018
However, semantics aside, we think that DXA can indeed serve as a reference standard for measuring muscle mass. Obviously, CT and MRI are advanced techniques that can and have been used to obtain important information such as muscle size/volume and more ...
Fanny Buckinx   +30 more
doaj   +1 more source

Genetic Variant in ACVR2B Is Associated with Lean Mass [PDF]

open access: yesMedicine & Science in Sports & Exercise, 2016
Low lean mass (LM) is a risk factor for chronic disease, a major cause of disability and diminished quality of life, and is a heritable trait. However, relatively few specific genetic factors have been identified as potentially influencing this trait.In this study, we selected 1493 single-nucleotide polymorphisms (SNP) in 155 candidate genes involved ...
J. Skye Nicholas   +8 more
openaire   +3 more sources

Meta-Analysis Examining the Importance of Creatine Ingestion Strategies on Lean Tissue Mass and Strength in Older Adults

open access: yesNutrients, 2021
Creatine supplementation in conjunction with resistance training (RT) augments gains in lean tissue mass and strength in aging adults; however, there is a large amount of heterogeneity between individual studies that may be related to creatine ingestion ...
Scott C. Forbes   +4 more
semanticscholar   +1 more source

Pitfalls in the measurement of muscle mass: a need for a reference standard

open access: yesJournal of Cachexia, Sarcopenia and Muscle, 2018
Background All proposed definitions of sarcopenia include the measurement of muscle mass, but the techniques and threshold values used vary. Indeed, the literature does not establish consensus on the best technique for measuring lean body mass. Thus, the
Fanny Buckinx   +30 more
doaj   +1 more source

Association of change in muscle mass assessed by D3‐creatine dilution with changes in grip strength and walking speed

open access: yesJournal of Cachexia, Sarcopenia and Muscle, 2020
Background Muscle mass declines with age. However, common assessments used to quantify muscle mass are indirect. The D3‐creatine (D3Cr) dilution method is a direct assessment of muscle mass; however, longitudinal changes have not been examined in ...
Kate A. Duchowny   +9 more
doaj   +1 more source

The Copenhagen Sarcopenia Study: lean mass, strength, power, and physical function in a Danish cohort aged 20–93 years

open access: yesJournal of Cachexia, Sarcopenia and Muscle, 2019
Despite no international consensus on the diagnostic criteria for sarcopenia, low lean mass, muscle strength, and physical function are important risk factors for disability, frailty, and mortality in older individuals, as well as in a wide range of ...
C. Suetta   +14 more
semanticscholar   +1 more source

Association between lean mass and adolescent idiopathic scoliosis: a meta-analysis

open access: yesBMC Musculoskeletal Disorders, 2023
Objective The objective of this meta-analysis was to evaluate the association between lean mass and adolescent idiopathic scoliosis (AIS). Methods English databases CENTRAL (The Cochrane Library and the Cochrane Back Review Group Trials Register ...
Wei Xu, Jiajie Zang, Fan Wu
doaj   +1 more source

Four pleiotropic loci associated with fat mass and lean mass

open access: yesInternational Journal of Obesity, 2020
Fat mass and lean mass are two biggest components of body mass. Both fat mass and lean mass are under strong genetic determinants and are correlated.We performed a bivariate genome-wide association meta-analysis of (lean adjusted) leg fat mass and (fat adjusted) leg lean mass in 12,517 subjects from 6 samples, and followed by in silico replication in ...
Yu Liu   +15 more
openaire   +4 more sources

Establishing the Link Between Lean Mass and Grip Strength Cut-points With Mobility Disability and Other Health Outcomes: Proceedings of the Sarcopenia Definition and Outcomes Consortium Conference.

open access: yesThe journals of gerontology. Series A, Biological sciences and medical sciences, 2019
BACKGROUND Lack of consensus on how to diagnose sarcopenia has limited the ability to diagnose this condition and hindered drug development. The Sarcopenia Definitions and Outcomes Consortium (SDOC) was formed to develop evidence-based diagnostic cut ...
P. Cawthon   +31 more
semanticscholar   +1 more source

Weight-adjusted lean body mass and calf circumference are protective against obesity-associated insulin resistance and metabolic abnormalities

open access: yesHeliyon, 2017
Background: To test the hypothesis that preserved muscle mass is protective against obesity-associated insulin resistance and metabolic abnormalities, we analyzed the relationship of lean body mass and computed tomography-assessed sectional areas of ...
Toshinari Takamura   +8 more
doaj   +1 more source

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