Results 121 to 130 of about 9,002 (304)
Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett +8 more
wiley +1 more source
Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina +11 more
wiley +1 more source
Teachability and Learnability Across Languages
Teachability and Learnability across Languages addresses key issues in second, foreign and heritage language acquisition, as well as in language teaching.Intro -- Teachability and Learnability across Languages -- Editorial page -- Title page -- Copyright
Keßler, Jörg-U. +3 more
core
, 2008 LEARNABILITY. The mathematical theory of language learnability (also known as learnability theory, grammar induction, or grammatical inference) deals with idealized “learning procedures ” for acquiring grammars on the basis of exposure to evidence about ...
Geoffrey K. Pullum
core
AgricultureReducing cumbersome mechanical control components is one of the trends of modern agricultural machinery towards a high degree of automation. Whether the control components of sugarcane harvesters can gradually be replaced by central control screens ...
Xiaoyu Wu, Sha Liu
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Emerging evidence suggests that low‐frequency neural oscillations are dynamically regulated by consciousness levels, with the recovery of low cortical activity potentially serving as a neurophysiological substrate for conscious emergence. Targeted enhancement of these low‐frequency rhythms in patients with disorders of consciousness
Chuan Xu +10 more
wiley +1 more source
Learnability of solutions to conjunctive queries [PDF]
, 2019 The problem of learning the solution space of an unknown formula has been studied inmultiple embodiments in computational learning theory. In this article, we study a familyof such learning problems; this family contains, for each relational structure ...
Chen, Hubie, Valeriote, M.
core
You ‘again’: an acquisition study on its restitutive reading with goal-PPs
GlossaAvailability of restitutive ‘again’ varies both cross-linguistically and language-internally. This creates an acquisition puzzle: For each change-of-state predicate, how do children know if a restitutive reading is possible?
Stella Christie, Ting Xu, William Snyder
doaj +2 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem +17 more
wiley +1 more source