Results 61 to 70 of about 691,780 (309)

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Effectiveness of psychological empowerment training program based on individual psychology Adler's theory on female-headed household’s learned helplessness [PDF]

Faṣlnāmah-i Farhang Mushavirah va Ravān/Darmānī, 2017
Purpose: The objective of this study was to determine the effectiveness of psychological empowerment training program based on individual psychology Adler's theory on female-headed household’s learned helplessness.
Alireza karimivakil, Abdollah Shafiabadi, kiiumars farahbakhsh, jalil younesi   +3 more
doaj   +1 more source

LEARNED HEPLESSNESS ANAK DALAM SITUASI ESKA (EKSPLOITASI SEKSUAL KOMERSIAL ANAK) : Studi Kasus Anak Dalam Situasi ESKA Di Kota Bandung [PDF]

, 2016
Penelitian ini bertujuan untuk mengetahui gambaran learned helplessness (Ketidakberdayaan) pada anak dalam situasi dan faktor-faktor apa saja yang ikut mempengaruhinya. Learned helplessness adalah kondisi bahwa individu merasa tidak mampu mengontrol (not
Wisena, Jaka Bagja Darma
core  

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Learned Helplessness Encountered by Michael Oher in the Blind Side Movie [PDF]

, 2014
Pamungkas, Dimas Probo. 2014. Learned Helplessness Encountered by Michael Oher in The Blind Side Movie. Study Program of English, Department of Languages and Literature, Faculty of Culture Studies, Universitas Brawijaya.
PAMUNGKAS, D. P. (DIMAS)
core   +2 more sources

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

The Influence of Attributional Beliefs On Indonesian EFL Learners’ Reading Comprehension

JEELS (Journal of English Education and Linguistics Studies), 2022
This research investigated how Indonesian EFL learners attributed their successes and failures in reading comprehension and whether or not there was any correlation between attributional beliefs and EFL learners’ monitoring strategies in reading.
Nancy Agatha Florida, Concilianus Laos Mbato   +1 more
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Lack of Antidepressant Effects of (2R,6R)-Hydroxynorketamine in a Rat Learned Helplessness Model: Comparison with (R)-Ketamine. [PDF]

Int J Neuropsychopharmacol, 2018
Background (R)-Ketamine exhibits rapid and sustained antidepressant effects in animal models of depression. It is stereoselectively metabolized to (R)-norketamine and subsequently to (2R,6R)-hydroxynorketamine in the liver.
Shirayama Y, Hashimoto K.
europepmc   +2 more sources

Beberapa Bentuk Perilaku Underachievement Dari Perspektif Teori Self Re-gulated Learning [PDF]

, 2005
Underachievement is generally caused by factors related to students behaviors which do not support their learning. This article discusses some behaviors leading to underachievement, namely amotivation, learned helplessness, self handicapping, and ...
Sunawan, S. (Sunawan)
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