Multimodal survival analysis of glioblastoma using whole-slide histopathology, gene expression, clinical variables and language-model-derived mutation features. [PDF]
Wang T, Alfaro J, Brennan PM, Rajan A.
europepmc +1 more source
The Lupus Damage Index Revision Program: Results From the Item Generation and Reduction Phases
Objective A data‐driven and expert/patient consensus‐based project to develop a revised Systemic Lupus International Collaborating Clinics (SLICC)/American College of Rheumatology (ACR) Damage Index (SDI) is under way supported by SLICC, ACR, and the Lupus Foundation of America. Our objective is to report the item generation and reduction phase results
Burak Kundakci +25 more
wiley +1 more source
MS-ConTab: multi-scale contrastive learning of mutation signatures for Pan-Cancer representation and stratification. [PDF]
Dou Y, Khadre A, Petreaca RC, Golrokh M.
europepmc +1 more source
Objective To evaluate utility of an artificial intelligence (AI) health coach for systemic sclerosis (SSc) self‐management and identify patterns associated with participant engagement. Methods We conducted a mixed methods study in which an AI health coach, powered by a large language model (LLM), was used to support self‐management for SSc.
Nirali Shah +4 more
wiley +1 more source
Multi-OCT-SelfNet: integrating self-supervised learning with multi-source data fusion for enhanced multi-class retinal disease classification. [PDF]
Jannat FE +5 more
europepmc +1 more source
Objective For cartilage morphology to serve as a scalable endpoint in clinical trials, analyses should be performed automatically without human interaction. To clinically validate artificial intelligence (AI)‐based analysis, we studied cartilage loss from MRI prior to knee replacement.
Felix Eckstein +3 more
wiley +1 more source
Histology-informed spatial domain identification through multi-view graph convolutional networks. [PDF]
Zhang H +11 more
europepmc +1 more source
Interstitial lung disease (IRD‐ILD) is a significant cause of morbidity and mortality in patients with inflammatory rheumatic disorders (IRD). High‐resolution computed tomography (HRCT) is widely considered the gold standard for the non‐invasive assessment of ILD; however, its interpretation is constrained by substantial inter‐observer variability and ...
Alexander Pfeil +7 more
wiley +1 more source
Facial cosmetic therapy use amongst patients with systemic sclerosis: an Australian cohort study
Objective Systemic sclerosis (SSc) is associated with numerous facial manifestations for which patients may engage in cosmetic therapies. It is unclear how patients with SSc use these therapies. This study sought to characterise patient engagement and experiences with cosmetic therapies for SSc‐related and non‐SSc‐related facial changes.
Zachary Warren +11 more
wiley +1 more source
Structure-aware retinal disentanglement reveals the genetic architecture of ocular and systemic diseases. [PDF]
Wei C +13 more
europepmc +1 more source

