Results 41 to 50 of about 356,546 (344)

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Medienkompetenz durch ‹Learning by Doing›?

open access: yesMedienPädagogik: Zeitschrift für Theorie und Praxis der Medienbildung
Lehrkräfte an berufsbildenden Schulen sollen über grundlegende Medienkompetenzen verfügen, um ihren Schüler:innen den Umgang mit digitalen Endgeräten medienpädagogisch zu vermitteln und deren Fähigkeiten und Fertigkeiten in diesem Bereich zu stärken ...
Johannes Schäfers
doaj   +1 more source

Reflection in Learning to Write an Academic Text. How Does Reflection Affect Observational Learning and Learning-by-Doing in a Research Synthesis Task?

open access: yesFrontiers in Education, 2019
In this study, we focused on the effect of reflection on different instructional methods, comparing observational learning and learning by doing, in the context of an academic writing task.
Janneke van der Loo   +2 more
doaj   +1 more source

The Development of Research Process for Pre-service Physics Teachers in Science Classroom Action Research Course using Learning by Doing [PDF]

open access: yesJournal of Humanities and Social Sciences Mahasarakham University, 2022
The objectives of this research were to 1) study the knowledge, understanding and competency in classroom research of preservice physics teachers who had received hands-on instructional activities, and 2) study the satisfaction of hands-on instructional ...
Duangjan kaewkongpan, Chisapath hoothong
doaj  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Unravelling learning by doing [PDF]

open access: yes, 2009
Scheele, F. [Promotor]Vleuten, C.P.M.
Teunissen, P.W.
core   +2 more sources

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Methodological Learning-by-Doing

open access: yesGrounded Theory Review: An International Journal, 2009
The experience of minus mentoring in learning classic grounded theory (CGT) is shared by many people over the world. The aim of this article is to share experiences of learning and using CGT.
Pernilla Pergert
doaj  

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Development of Student Worksheets for Economics Subjects Based on Learning by Doing

open access: yesTekno - Pedagogi
This research aims to develop student worksheets based on Learning by Doing in learning Economics subjects for class X students at Senior High School 5 Jambi City.
Suratno Suratno
doaj   +1 more source

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