Results 81 to 90 of about 1,606,312 (290)

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

Online Reinforcement Learning for Dynamic Multimedia Systems

, 2009
In our previous work, we proposed a systematic cross-layer framework for dynamic multimedia systems, which allows each layer to make autonomous and foresighted decisions that maximize the system's long-term performance, while meeting the application's ...
Mastronarde, Nicholas, van der Schaar, Mihaela   +1 more
core   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Tumour nuclear size heterogeneity as a biomarker for post-radiotherapy outcomes in gynecological malignancies

Physics and Imaging in Radiation Oncology
Background and Purpose:: Radiotherapy targets DNA in cancer cell nuclei. Radiation dose, however, is prescribed to a macroscopic target volume assuming uniform distribution, failing to consider microscopic variations in dose absorbed by individual nuclei.
Yujing Zou, Harry Glickman, Manuela Pelmus, Farhad Maleki, Boris Bahoric, Magali Lecavalier-Barsoum, Shirin A. Enger   +6 more
doaj   +1 more source

Determination of Flow Parameters of a Water Flow Around an AUV Body

Robotics, 2019
Autonomous underwater vehicles (AUVs) have changed the way marine environment is surveyed, monitored and mapped. Autonomous underwater vehicles have a wide range of applications in research, military, and commercial settings.
Julian Hoth, Wojciech Kowalczyk
doaj   +1 more source

Schema Independent Relational Learning

, 2017
Learning novel concepts and relations from relational databases is an important problem with many applications in database systems and machine learning. Relational learning algorithms learn the definition of a new relation in terms of existing relations ...
Abiteboul S., Anderson M., Arias M., Kraska T., Muggleton S., Muggleton S., Muggleton S., Yin X.   +7 more
core   +1 more source

Advancing Age Modulates Associations Between Cognitive Impairment and Brain Volumes in Early MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Cognitive impairment is common in multiple sclerosis (MS), but manifestations following the first demyelinating event are relatively unexplored. We investigated cross‐sectional associations between magnetic resonance imaging (MRI)–derived brain volumes and the presence of cognitive impairment outcomes five years after the first ...
Piriyankan Ananthavarathan, Marco Pitteri, Michael Foster, Sara Collorone, Sara Salama, Elisa Colato, Ferran Prados, Baris Kanber, Marios Yiannakas, Claudia A. M. Gandini Wheeler‐Kingshott, Indran Davagnanam, Frederik Barkhof, Declan Chard, Olga Ciccarelli, Ahmed Toosy   +14 more
wiley   +1 more source

BOBM: an adaptive deep learning framework for extended-window sepsis prediction with cross-institutional generalizability

Frontiers in Medicine
IntroductionSepsis, a life-threatening and costly condition, necessitates early detection for effective management. However, diagnostic and therapeutic delays are common.
Wanxuan Li, Wanxuan Li, Kai Xiao, Boyuan Gu, Boyuan Gu, Haoyu Zheng, Haoyu Zheng, Dan Shao, Ren Mo, Ren Mo, Qiang Wu, Qiang Wu, Qiong Yang   +12 more
doaj   +1 more source

A Learning Algorithm for Synfire Chains [PDF]

, 2001
Neurobiological studies indicate very precise temporal behavior of neuron firings. Abeles [1] has recorded spike timing of different cortical cells and, in particular, has observed the following level of precision: when a neuron A frres, neuron B would frre 151ms later and neuron C would fire precisely 289ms after that—with aprecision across trials of ...
openaire   +2 more sources

A learning algorithm for boltzmann machines [PDF]

Cognitive Science, 1985
The computational power of massively parallel networks of simple processing elements resides in the communication bandwidth provided by the hardware connections between elements. These connections can allow a significant fraction of the knowledge of the system to be applied to an instance of a problem in a very short time.
David H. Ackley, Geoffrey E. Hinton, Terrence J. Sejnowski   +2 more
openaire   +1 more source