Results 81 to 90 of about 402,431 (257)

Variational Bayes machine learning for risk adjustment of general outcome indicators with examples in urology

npj Digital Medicine
Risk adjustment is often necessary for outcome quality indicators (QIs) to provide fair and accurate feedback to healthcare professionals. However, traditional risk adjustment models are generally oversimplified and not equipped to disentangle complex ...
Harvey Jia Wei Koh, Dragan Gašević, David Rankin, Stephane Heritier, Mark Frydenberg, Stella Talic   +5 more
doaj   +1 more source

The Impact of Random Models on Standardized Clustering Similarity

IEEE Access
Clustering similarity measures are essential for evaluating clustering results and ensuring diversity in multiple clusterings of the same dataset. Common indices like the Mutual Information (MI) and Rand Index (RI) are biased towards smaller clusters and
Kai Klede, Thomas R. Altstidl, Dario Zanca, Bjorn M. Eskofier   +3 more
doaj   +1 more source

Learning Analytics Community Exchange: Evidence Hub [PDF]

, 2016
This poster sets out the background and development of the LACE Evidence Hub, a site that gathers evidence about learning analytics in an accessible form.
Clow, Doug, Ferguson, Rebecca
core  

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

A multi-method psychometric assessment of the affinity for technology interaction (ATI) scale

Computers in Human Behavior Reports, 2020
In order to develop valid and reliable instruments, psychometric validation should be conducted as an iterative process that “requires a multi-method assessment” (Schimmack, 2019, p. 4).
Olga Lezhnina, Gábor Kismihók
doaj   +1 more source

Learning analytics with learning and analytics : advancing student agency analytics

, 2022
unknown ...
openaire   +2 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Wearable Current-Based ECG Monitoring System with Non-Insulated Electrodes for Underwater Application

Applied Sciences, 2017
The second most common cause of diving fatalities is cardiovascular diseases. Monitoring the cardiovascular system in actual underwater conditions is necessary to gain insights into cardiac activity during immersion and to trigger preventive measures. We
Stefan Gradl, Tobias Cibis, Jasmine Lauber, Robert Richer, Ruslan Rybalko, Norman Pfeiffer, Heike Leutheuser, Markus Wirth, Vinzenz von Tscharner, Bjoern M. Eskofier   +9 more
doaj   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source