Results 81 to 90 of about 99,515 (314)

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Harmonizing the CBCL and SDQ ADHD scores by using linear equating, kernel equating, item response theory and machine learning methods

Frontiers in Psychology
IntroductionA problem that applied researchers and practitioners often face is the fact that different institutions within research consortia use different scales to evaluate the same construct which makes comparison of the results and pooling ...
Miljan Jović, Maryam Amir Haeri, Andrew Whitehouse, Stéphanie M. van den Berg   +3 more
doaj   +1 more source

Discourse-centric learning analytics: mapping the terrain [PDF]

, 2015
There is an increasing interest in developing learning analytic techniques for the analysis, and support of, high quality learning discourse. This paper maps the terrain of discourse-centric learning analytics (DCLA), outlining the distinctive ...
Knight, Simon, Littleton, Karen, Littleton, K, Knight, S   +3 more
core   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Benchmarking Foot Trajectory Estimation Methods for Mobile Gait Analysis

Sensors, 2017
Mobile gait analysis systems based on inertial sensing on the shoe are applied in a wide range of applications. Especially for medical applications, they can give new insights into motor impairment in, e.g., neurodegenerative disease and help objectify ...
Julius Hannink, Malte Ollenschläger, Felix Kluge, Nils Roth, Jochen Klucken, Bjoern M. Eskofier   +5 more
doaj   +1 more source

Vagus activation by Cold Face Test reduces acute psychosocial stress responses

Scientific Reports, 2022
Chronic stress is linked to dysregulations of the two major stress pathways—the sympathetic nervous system and the hypothalamic-pituitary-adrenal (HPA) axis, which could for example result from maladaptive responses to repeated acute stress.
Robert Richer, Janis Zenkner, Arne Küderle, Nicolas Rohleder, Bjoern M. Eskofier   +4 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

A Conceptual Framework for Mobile Augmented-Reality Storytelling to Support Collaborative Language Learning in Vocational Education and Training

Multimodal Technologies and Interaction
Augmented Reality (AR) has been found to produce significant effects on individual learning outcomes but its impact on collaborative applications remains moderate.
Eirini Maria Paraskevioti, Athanasios Christopoulos, Stylianos Mystakidis, Mikko-Jussi Laakso, Tapio Salakoski   +4 more
doaj   +1 more source

A Deep Learning Approach to Position Estimation from Channel Impulse Responses

Sensors, 2019
Radio-based locating systems allow for a robust and continuous tracking in industrial environments and are a key enabler for the digitalization of processes in many areas such as production, manufacturing, and warehouse management.
Arne Niitsoo, Thorsten Edelhäußer, Ernst Eberlein, Niels Hadaschik, Christopher Mutschler   +4 more
doaj   +1 more source

Creating data for learning analytics ecosystems [PDF]

, 2021
Learning is a complex process that involves rich interactions between people, politics, places, and increasingly, technology. Using clickstream data to provide deep insights into learning requires care and a system-wide approach.
Webb, M, Silvers, A, Kitto, K, Whitmer, J   +3 more
core