Results 291 to 300 of about 6,561,272 (426)

Frequency and Early Predictors of Cognitive Deterioration in Amyotrophic Lateral Sclerosis: A Longitudinal Population‐Based Study

open access: yesAnnals of Neurology, EarlyView.
Objective The objective is to evaluate cognitive and behavioral progression and identify early predictors of these changes in a cohort of amyotrophic lateral sclerosis (ALS) patients. Methods A total of 161 ALS patients were tested at diagnosis (T0), and 107 were re‐tested after 1 year (T1) using cognitive/behavioral tests. All patients underwent whole‐
Barbara Iazzolino   +13 more
wiley   +1 more source

Regional Cerebral Atrophy Contributes to Personalized Survival Prediction in Amyotrophic Lateral Sclerosis: A Multicentre, Machine Learning, Deformation‐Based Morphometry Study

open access: yesAnnals of Neurology, EarlyView.
Objective Accurate personalized survival prediction in amyotrophic lateral sclerosis is essential for effective patient care planning. This study investigates whether grey and white matter changes measured by magnetic resonance imaging can improve individual survival predictions.
Isabelle Lajoie   +3 more
wiley   +1 more source

Brain Metabolic Features of FUS‐ALS: A 2‐[18F]FDG‐PET Study

open access: yesAnnals of Neurology, EarlyView.
Objective We aimed at evaluating the brain metabolic features of fused in sarcoma amyotrophic lateral sclerosis (FUS‐ALS) compared with sporadic ALS (sALS), using 2‐[fluorine‐18] fluoro‐2‐deoxy‐D‐glucose positron emission tomography (2‐[18F]FDG‐PET). Methods We employed the 2‐sample t‐test model of SPM12, implemented in MATLAB, to compare 12 FUS‐ALS ...
Antonio Canosa   +24 more
wiley   +1 more source

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