Results 51 to 60 of about 16,249,535 (214)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Partisipasi Pembelajaran Bahasa Indonesia Kelas XI dalam Program Habit-Forming MAN 2 Samarinda
Diglosia, 2023 The habit-forming program is designed by schools/madrasas to accustom learners to habituation. Indonesian language learning materials can participate in habit-forming programs.
Rinda Cahya Mudiawati +2 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Jurnal Inovasi Pendidikan dan SainsThis classroom action research was conducted at SDN 91/VI Rantau Panjang VI. The objective of the study was to improve the learning process and outcomes of Pancasila Education in Grade III through the implementation of the Discovery Learning model.
Saviny Alqorama Ayda +2 more
doaj +1 more source
Expression and connection : the integration of the reflective learning process and the writing process into social network sites [PDF]
, 2011 A number of instructors have recently adopted social network sites (SNSs) for learning. However, the learning design of SNSs often remains at a preliminary level similar to a personal log book because it does not properly include reflective learning ...
Son, Jeong-Bae, Park, Ji Yong
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
About the Role of the Digital Technologies in the Education in Mathematics [PDF]
Икономика и компютърни науки, 2022 The purpose of this article is to observe and compare the applications of some digital technologies in the mathematical education. The research is limited to two different types of approach.
Radan Miryanov
doaj
Using Hidden Markov Models for the accurate linguistic analysis of process model activity labels [PDF]
, 2019 Many process model analysis techniques rely on the accurate analysis of the natural language contents captured in the models’ activity labels. Since these labels are typically short and diverse in terms of their grammatical style, standard natural ...
Reijers, Hajo A.; id_orcid +8 more
core +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Ψυχολογία: το Περιοδικό της Ελληνικής Ψυχολογικής Εταιρείας, 2020 IS AVAILABLE IN THE ...
Annette Schick
doaj +1 more source