Results 91 to 100 of about 1,099,722 (325)

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Effective Lightweight Learning-to-Rank Method Using Unified Term Impacts

open access: yesIEEE Access, 2020
In this study, we propose and evaluate a novel learning-to-rank (L2R) approach that produces results on par with those of the state-of-the-art L2R methods while being computationally effective.
Sheila Da N. Silva   +3 more
doaj   +1 more source

Image restoration with group sparse representation and low‐rank group residual learning [PDF]

open access: gold, 2023
Zhaoyuan Cai   +5 more
openalex   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

A Multi-Perspective Learning to Rank Approach to Support Children's Information Seeking in the Classroom [PDF]

open access: green, 2023
Garrett Allen   +4 more
openalex   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Learning to rank quantum circuits for hardware-optimized performance enhancement [PDF]

open access: yesQuantum
We introduce and experimentally test a machine-learning-based method for ranking logically equivalent quantum circuits based on expected performance estimates derived from a training procedure conducted on real hardware.
Gavin S. Hartnett   +5 more
doaj   +1 more source

Interplay between RNA‐protein interactions and RNA structures in gene regulation

open access: yesFEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko   +2 more
wiley   +1 more source

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