Results 101 to 110 of about 1,093,151 (324)
Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications
FEBS Open Bio, EarlyView.This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley +1 more source
Ranking learning-to-rank methods
, 2017 We present a cross-benchmark comparison of learning-to-rank methods using two evaluation measures: the Normalized Winning Number and the Ideal Winning Number. Evaluation results of 87 learning-to-rank methods on 20 datasets show that ListNet, SmoothRank, FenchelRank, FSMRank, LRUF and LARF are Pareto optimal learning-to-rank methods, listed in ...
Hiemstra, D., Tax, N., Bockting, S.
openaire +1 more source
DrugE-Rank: Predicting Drug-Target Interactions by Learning to Rank [PDF]
, 2018 Identifying drug-target interactions is crucial for the success of drug discovery. Approaches based on machine learning for this problem can be divided into two types: feature-based and similarity-based methods. By utilizing the "Learning to rank" framework, we propose a new method, DrugE-Rank, to combine these two different types of methods for ...
Jieyao, Deng +3 more
openaire +2 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Epilepsy is increasingly associated with immune dysregulation and inflammation. The T cell receptor (TCR), a key mediator of adaptive immunity, shows repertoire alterations in various immune‐mediated diseases. The unique TCR sequence serves as a molecular barcode for T cells, and clonal expansion accompanied by reduced overall TCR ...
Yong‐Won Shin +12 more
wiley +1 more source
PASSerRank: Prediction of allosteric sites with learning to rank. [PDF]
J Comput Chem, 2023 Tian H, Xiao S, Jiang X, Tao P.
europepmc +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Introduction Neuronal pentraxin 2 (NPTX2) is a synaptic protein involved in synaptic plasticity and regulation of neuronal excitability. Lower baseline cerebrospinal fluid (CSF) NPTX2 levels have been shown to be associated with an earlier onset of mild cognitive impairment (MCI), a pre‐dementia syndrome, even after CSF Alzheimer's Disease (AD)
Juan P. Vazquez +12 more
wiley +1 more source
RankCSE: Unsupervised Sentence Representations Learning via Learning to Rank [PDF]
, 2023 Jiduan Liu +8 more
openalex +1 more source
Diffusion Tractography Biomarker for Epilepsy Severity in Children With Drug‐Resistant Epilepsy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To develop a novel deep‐learning model of clinical DWI tractography that can accurately predict the general assessment of epilepsy severity (GASE) in pediatric drug‐resistant epilepsy (DRE) and test if it can screen diverse neurocognitive impairments identified through neuropsychological assessments.
Jeong‐Won Jeong +7 more
wiley +1 more source
Replace Scoring with Arrangement: A Contextual Set-to-Arrangement Framework for Learning-to-Rank [PDF]
, 2023 Jiarui Jin +7 more
openalex +1 more source
Higher Amyloid and Tau Burden Is Associated With Faster Decline on a Digital Cognitive Test
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective A 2‐min digital clock‐drawing test (DCTclock) captures more granular features of the clock‐drawing process than the pencil‐and‐paper clock‐drawing test, revealing more subtle deficits at the preclinical stage of Alzheimer's disease (AD). A previous cross‐sectional study demonstrated that worse DCTclock performance was associated with
Jessie Fanglu Fu +16 more
wiley +1 more source