Results 101 to 110 of about 1,099,722 (325)

Homologous expression and purification of human HAX‐1 for structural studies

open access: yesFEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

InRank: Incremental Low-Rank Learning [PDF]

open access: green, 2023
Jiawei Zhao   +4 more
openalex   +1 more source

Ranking learning-to-rank methods

open access: yes, 2017
We present a cross-benchmark comparison of learning-to-rank methods using two evaluation measures: the Normalized Winning Number and the Ideal Winning Number. Evaluation results of 87 learning-to-rank methods on 20 datasets show that ListNet, SmoothRank, FenchelRank, FSMRank, LRUF and LARF are Pareto optimal learning-to-rank methods, listed in ...
Hiemstra, D., Tax, N., Bockting, S.
openaire   +1 more source

DrugE-Rank: Predicting Drug-Target Interactions by Learning to Rank [PDF]

open access: yes, 2018
Identifying drug-target interactions is crucial for the success of drug discovery. Approaches based on machine learning for this problem can be divided into two types: feature-based and similarity-based methods. By utilizing the "Learning to rank" framework, we propose a new method, DrugE-Rank, to combine these two different types of methods for ...
Jieyao, Deng   +3 more
openaire   +2 more sources

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

open access: yesFEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart   +4 more
wiley   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

open access: yesFEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman   +4 more
wiley   +1 more source

Learning to Exploit Different Translation Resources for Cross Language Information Retrieval

open access: yesInternational Journal of Information and Communication Technology Research, 2014
One of the important factors that affects the performance of Cross Language Information Retrieval(CLIR) is the quality of translations being employed in CLIR. In order to improve the quality of translations, it is important to exploit available resources
Hosein Azarbonyad   +2 more
doaj  

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