Results 111 to 120 of about 1,099,722 (325)

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Automated Generation of Hybrid Metaheuristics Using Learning-to-Rank

Algorithms
Metaheuristic algorithms, due to their superior global exploration capabilities and applicability, have emerged as critical tools for addressing complicated optimization tasks.
Xinru Xue, Ting Shu, Jinsong Xia
doaj   +1 more source

Systemic T Cell Receptor Profiling Reveals Adaptive Immune Activation and Potential Immune Signatures of Diagnosis and Brain Atrophy in Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy is increasingly associated with immune dysregulation and inflammation. The T cell receptor (TCR), a key mediator of adaptive immunity, shows repertoire alterations in various immune‐mediated diseases. The unique TCR sequence serves as a molecular barcode for T cells, and clonal expansion accompanied by reduced overall TCR ...
Yong‐Won Shin, Sang Bin Hong, Yong Woo Shin, Inpyeong Hwang, Jaeseong Oh, Jihyeon Choi, Narae Kim, Jangsup Moon, Keun‐Hwa Jung, Kyung‐Il Park, Ki‐Young Jung, Kon Chu, Sang Kun Lee   +12 more
wiley   +1 more source

A File-Statement Approach for Bug Localization: Optimizing IRBL and Combination Strategy

IEEE Access
One of the main objectives of software testing is to locate the position of bugs. Bug localization is generally categorized into statement-level and file-level localization.
Zhonghao Guo, Xinyue Xu, Xiangxian Chen, Chenge Geng   +3 more
doaj   +1 more source

Online Learning to Rank in Stochastic Click Models [PDF]

, 2017
Masrour Zoghi, Tomáš Tunys, Mohammad Ghavamzadeh, Branislav Kveton, Csaba Szepesvári, Zheng Wen   +5 more
openalex   +1 more source

CSF Levels of NPTX2 Are Associated With Less Brain Atrophy Over Time in Cognitively Unimpaired Individuals

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Neuronal pentraxin 2 (NPTX2) is a synaptic protein involved in synaptic plasticity and regulation of neuronal excitability. Lower baseline cerebrospinal fluid (CSF) NPTX2 levels have been shown to be associated with an earlier onset of mild cognitive impairment (MCI), a pre‐dementia syndrome, even after CSF Alzheimer's Disease (AD)
Juan P. Vazquez, Corinne Pettigrew, Yuxin Zhu, Claire Anderson, Guray Erus, Christos Davatzikos, Michael Miller, Abhay Moghekar, Sungtaek Oh, Chan‐Hyun Na, Marilyn Albert, Paul Worley, Anja Soldan   +12 more
wiley   +1 more source

Learning to rank query expansion terms for COVID-19 scholarly search. [PDF]

J Biomed Inform, 2023
Khader A, Ensan F.
europepmc   +1 more source

Learning to rank

, 2020
Sıralama ögrenimi örnek verileri kullanarak bunlardan bir sıralama modeli oluşturanmakine ögrenimi metotlarıdır. Bu model dökümanları önemine ya da uygunluğunabağlı olarak sıralayabilir. Bir çok Bilgiye Erişim teknolojisinin temelinde sıralama vardır.Bu yuzden Sıralama öğrenimi teknolojisi ile varolan bu teknolojiler daha da iyileştirilebilir.Sıralama ...
openaire   +1 more source

Diffusion Tractography Biomarker for Epilepsy Severity in Children With Drug‐Resistant Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To develop a novel deep‐learning model of clinical DWI tractography that can accurately predict the general assessment of epilepsy severity (GASE) in pediatric drug‐resistant epilepsy (DRE) and test if it can screen diverse neurocognitive impairments identified through neuropsychological assessments.
Jeong‐Won Jeong, Min‐Hee Lee, Hiroshi Uda, Yoon Ho Hwang, Michael Behen, Aimee Luat, Csaba Juhász, Eishi Asano   +7 more
wiley   +1 more source