Results 101 to 110 of about 419,205 (270)
Bayesian Estimation Improves Prediction of Outcomes After Epilepsy Surgery
ABSTRACT We estimated the statistical power of studies predicting seizure freedom after epilepsy surgery. We extracted data from a Cochrane meta‐analysis. The median power across all studies was 14%. Studies with a median sample size or less (n ≤ 56) and a statistically significant result exaggerated the true effect size by a factor of 5.4, while the ...
Adam S. Dickey +4 more
wiley +1 more source
To address the issue that polynomial approximation methods strongly depend on the analytical form of the objective function, this study proposes a new minimax polynomial approximation method based on the Chebyshev equioscillation theorem.
Letong Zhou, Liguo Zhao
doaj +1 more source
The star centroid estimation is the most important operation, which directly affects the precision of attitude determination for star sensors. This paper presents a theoretical study of the systematic error introduced by the star centroid estimation ...
Jingyan Song +3 more
doaj +1 more source
Effects of Biological Sex and Age on Cerebrospinal Fluid Markers—A Retrospective Observational Study
ABSTRACT Objective Cerebrospinal fluid (CSF) analysis is a key diagnostic tool for neurological diseases. To date, only a few studies have investigated in larger cohorts the effect of age and biological sex on diagnostic markers extracted from CSF. Methods For this retrospective observational study, 4163 CSF findings (2012–2020) were evaluated.
Isabel‐Sophie Hafer +3 more
wiley +1 more source
Continuous and discrete least-squares approximation by radial basis functions on spheres
Let \(S^n\) be the \(n\)-dimensional sphere in \(\mathbb R^n\) and \(A=\{U_j,\psi_j\}_{j=1}^m\) be an atlas for \(S^n\), i.e. open sets \(U_j\subset S^n\) cover \(S^n\), \(\psi_j\) are homeomorphic from \(U_j\) to the unit ball \(B(0,1)\subset \mathbb R^n\) and \(\psi_i\circ \psi_j^{-1}\) are \(C^{\infty}\) on \(\psi_j(U_j\cap U_i)\). Let \(\{\chi_j\}_{
Le Gia, Q. T. +3 more
openaire +3 more sources
Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler +20 more
wiley +1 more source
Stable and Accurate Least Squares Radial Basis Function Approximations on Bounded Domains
The computation of global radial basis function (RBF) approximations requires the solution of a linear system which, depending on the choice of RBF parameters, may be ill-conditioned. We study the stability and accuracy of approximation methods using the Gaussian RBF in all scaling regimes of the associated shape parameter.
Ben Adcock, Daan Huybrechs, Cecile Piret
openaire +3 more sources
Neuroinflammation in GAD65 Antibody‐Associated Epilepsy Measured Using [18F]DPA‐714 PET/MRI
ABSTRACT The timing for initiating immunotherapy in patients with glutamic acid decarboxylase 65 (GAD65) antibody‐associated epilepsy is a challenge. We used the translocator protein radioligand [18F]DPA‐714 and PET to evaluate brain microglial activation.
Jingjing Chen +10 more
wiley +1 more source
Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
Numerical Implementation of Meshless Methods for Beam Problems
For solving a partial different equation by a numerical method, a possible alternative may be either to use a mesh method or a meshless method. A flexible computational procedure for solving 1D linear elastic beam problems is presented that currently ...
Rosca V. E., Leitāo V. M. A.
doaj +1 more source

