Results 41 to 50 of about 658,329 (307)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

An adapted version of the element-wise weighted total least squares method for applications in chemometrics [PDF]

open access: yes, 2007
The Maximum Likelihood PCA (MLPCA) method has been devised in chemometrics as a generalization of the well-known PCA method in order to derive consistent estimators in the presence of errors with known error distribution.
Markovsky, Ivan   +2 more
core  

LEAST – SQUARES METHOD FOR ESTIMATING DIFFUSION COEFFICIENT

open access: yesInternational Journal of Industrial Engineering and Production Research, 2007
Determining the diffusion coefficient based on the solution of the linear inverse problem of the parameter estimation by using the Least-square method is presented.
Abdolsadeh Neisy
doaj  

Different methods of estimation for the one parameter Akash distribution

open access: yesCumhuriyet Science Journal, 2020
Akash distribution is a mixture of an exponential distribution and a gamma distribution with certain mixing proportions. Although the maximum likelihood estimation method has been proposed for the Akash distribution, there is no comprehensive comparison ...
Caner Tanış, Kadir Karakaya
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

NARX-based nonlinear system identification using orthogonal least squares basis hunting [PDF]

open access: yes, 2008
An orthogonal least squares technique for basis hunting (OLS-BH) is proposed to construct sparse radial basis function (RBF) models for NARX-type nonlinear systems.
Wang, X.X.   +2 more
core   +1 more source

INSTANTANEOUS FREQUENCY ESTIMATION USING A LEAST SQUARES TIME-FREQUENCY METHOD

open access: yesElectrica, 2004
We present a method for estimating the instantaneous frequency of a signal. This method involves the calculation of a time-frequency energy density of the signal, then obtaining an instantaneous frequency estimation from this joint density.
Mahmut ÖZTÜRK, Aydın AKAN
doaj   +2 more sources

Least – Squares Method For Estimating Diffusion Coefficient

open access: yesInternational Journal of Industrial Engineering and Production Research, 2008
: Determination of the diffusion coefficient on the base of solution of a linear inverse problem of the parameter estimation using the Least-square method is presented in this research.
A. Neisy
doaj  

Least Squares Method for Solving Fuzzy LR Interval Algebraic Linear Systems

open access: yesFuzzy Information and Engineering, 2022
We first investigate the solvability conditions of fuzzy LR interval algebraic linear systems with fuzzy LR interval coefficient matrix and fuzzy LR interval hand-right vector.
Mehrnoosh Salari   +2 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

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