Results 51 to 60 of about 1,208,864 (273)

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Benchmark study of three statistical methods for six intact rock failure criteria constrained by different rock strength data

Underground Space
To reduce the impact of potential strength outliers on parameter estimation, statistical methods based on the least median square and least absolute deviation have been proposed as alternatives to the traditional least square method.
Peng-fei He, Xin Li, Xu-long Yao, Zhi-gang Tao, Yan-ting Du   +4 more
doaj   +1 more source

Comparison of Squared Msplit Method Vs. Absolute Msplit Method - Case Study [PDF]

Geodetski Glasnik
In this paper we analyse and compare two modern methods of deformation analysis: the squared Msplit method and the absolute Msplit method. The comparison is made on cases of simulated and actually measured horizontal geodetic networks. The squared Msplit
Klemen Kregar, Žan Pleterski, Gašper Rak, Muamer Đidelija, Amir Hajdar, Tomaž Ambrožič   +5 more
doaj   +1 more source

Inflation uncertainty and economic growth: evidence from the LAD ARCH model [PDF]

, 2011
In this paper, we combined the panel data and least absolute deviation autoregressive conditional heteroscedastic (ARCH) (L 1-ARCH) model to infer on the relationship between inflation uncertainty and economic growth in five emerging market economies ...
Baharumshah, Ahmad Zubaidi, Hamzah, Nor Aishah, Muhammad Sabri, Shamsul Rijal   +2 more
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

تاثیر انرژی­های تجدیدپذیر بر منحنی زیست محیطی کوزنتسی در ایران [PDF]

Quarterly Journal of Applied Theories of Economics, 2015
رشد اقتصادی، هدف اصلی بسیاری از سیاست­های اقتصادی دولت­هاست. با این حال، رشد اقتصادی سریع،  باعث ایجاد زیان­های جدی بر محیط زیست می­شود. از این رو، یک تضاد بالقوه بین سیاست­های اقتصادی و وضعیت محیط زیست وجود دارد که در قالب منحنی زیست محیطی کوزنتس بیان ...
علی حسین استادزاد, پریسا بهلولی   +1 more
doaj  

Pengendalian Koefisien Regresi Least Absolute Deviation pada Rentang Bermakna Menggunakan Program Linier [PDF]

, 2018
So far, regression analysis is used to model the mean of response variable as a function of some independent variables, using the least squares (LS) method. In general, the LS method is able to describe well the measure of central tendency, however it is
Rochman, N. (Nur), Setyono, S. (Setyono), Soleh, A. M. (Agus)   +2 more
core  

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

ROBUST GEOGRAPHICALLY WEIGHTED REGRESSION WITH LEAST ABSOLUTE DEVIATION (LAD) ESTIMATION AND M-ESTIMATION ON GRDP OF WEST JAVA PROVINCE

Barekeng
Geographically Weighted Regression (GWR) is an analytical method for data that contains spatial heterogeneity effects. However, parameter estimation in the GWR model has a weakness, namely it is prone to outliers and can cause the parameter estimation to
Prizka Rismawati Arum, Mohammad Ridwan, Ina Alfidayanti, Rochdi Wasono   +3 more
doaj   +1 more source

Weighted Least Absolute Deviation Lasso Estimator [PDF]

Communications for Statistical Applications and Methods, 2011
The linear absolute shrinkage and selection operator(Lasso) method improves the low prediction accuracy and poor interpretation of the ordinary least squares(OLS) estimate through the use of L1 regularization on the regression coefficients. However, the Lasso is not robust to outliers, because the Lasso method minimizes the sum of squared residual ...
openaire   +1 more source