Results 81 to 90 of about 1,208,864 (273)

Linearization of randomly weighted empiricals under long range dependence with application to nonlinear regression quantiles [PDF]

open access: yes, 2000
This paper discusses some asymptotic uniform linearity results of randomly weighted empirical processes based on long range dependent random variables+ These results are subsequently used to linearize nonlinear regression quantiles in a nonlinear ...
Mukherjee, Kanchan
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

تحديد العوامل المؤثرة على مرض السكري من خلال تحليل الانحدار [PDF]

open access: yesمجلة ابحاث كلية التربية الاساسية
Globally, diabetes has been shown to be a significant cause of both death and morbidity, affecting a wide range of populations irrespective of age, gender, or region.
HUSSEIN HASHEM   +2 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

A NEW METHOD OF ROBUST LINEAR REGRESSION ANALYSIS: SOME MONTE CARLO EXPERIMENTS [PDF]

open access: yes
This paper has elaborated upon the deleterious effects of outliers and corruption of dataset on estimation of linear regression coefficients by the Ordinary Least Squares method.
Sudhanshu Kumar MISHRA
core   +3 more sources

Nonparametric LAD Cointegrating Regression [PDF]

open access: yes
We deal with nonparametric estimation in a nonlinear cointegration model whose regressor and dependent variable can be contemporaneously correlated. The asymptotic properties of the Nadaraya-Watson estimator are already examined in the literature.
Toshio Honda
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Least absolute deviations learning of multiple tasks

open access: yesJournal of Industrial & Management Optimization, 2018
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Xue, Wei, Zhang, Wensheng, Yu, Gaohang
openaire   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

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