Results 111 to 120 of about 701,217 (307)

A Note on Numerical Estimation of Sato’s Two-Level CES Production Function [PDF]

In this paper Sato’s two-level CES production function has been estimated by nonlinear regression carried out through five different methods of optimization, namely, the Hooke-Jeeves Pattern Moves (HJPM), the Hooke-Jeeves-Quasi-Newton (HJQN), the ...
Mishra, SK
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

The Cosmic Microwave Background Spectrum and a Determination of Fractal Space Dimensionality

, 2008
The possibility to constrain fractal space dimensionality from Astrophysics and other areas is briefly reviewed. Assuming such dimensionality to be $3 + \epsilon$, a limit to $\epsilon$ can be inferred from COBE satellite data. The available data for the
Bhanot, Caruso, Caruso, Caruso, COBE Collaboration, Ehrenfest, F. Caruso, Fixsen, Jarlskog, Mandelbrot, Petkov, Schäfer, Tangherlini, Torres, V. Oguri   +14 more
core   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Diffusion of information technology, internet use and the demand of heterogeneous labor [PDF]

This paper analyzes the link between the diffusion of information- and communication technology (ICT) and both the skill structure and employment expectations of the different skill categories.
Falk, Martin
core  

Inhibition of Classical and Alternative Complement Pathway by Ravulizumab and Eculizumab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the feasibility of classical (CH50) and alternative (AH50) complement pathway activity as potential biomarkers for treatment guidance and monitoring during therapy with ravulizumab in patients with generalized myasthenia gravis (gMG) and compare these to therapeutic drug monitoring under eculizumab.
Lea Gerischer, Frauke Stascheit, Maximilian Mönch, Paolo Doksani, Carla Dusemund, Meret Herdick, Philipp Mergenthaler, Maike Stein, Amani Suboh, Jutta Schröder‐Braunstein, Guido Wabnitz, Jan D. Lünemann, Sophie Lehnerer, Sarah Hoffmann, Andreas Meisel   +14 more
wiley   +1 more source

Detailed comparison of Milky Way models based on stellar population synthesis and SDSS star counts at the north Galactic pole

, 2012
We test the ability of the TRILEGAL and Besancon models to reproduce the CMD of SDSS data at the north Galactic pole (NGP). We show that a Hess diagram analysis of colour-magnitude diagrams is much more powerful than luminosity functions (LFs) in ...
Gao, Shuang, Grebel, Eva K., Just, Andreas   +2 more
core   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Utility score mapping from FACT-G to EQ-5D-5L and SF-6Dv2 in breast and colorectal cancer patients: a focus on beta mixture models

Health and Quality of Life Outcomes
Objective To develop algorithms mapping the Functional Assessment of Cancer Therapy—General Scale (FACT-G) onto the EuroQol 5-Dimension 5-level (EQ-5D-5 L) and the Short-Form Six-Dimension version 2 (SF-6Dv2) for patients with breast or colorectal ...
Thomas G. Poder, Hosein Ameri
doaj   +1 more source

Infinite Density at the Median and the Typical Shape of Stock Return Distributions [PDF]

Statistics are developed to test for the presence of an asymptotic discontinuity (or infinite density or peakedness) in a probability density at the median. The approach makes use of work by Knight (1998) on L_1 estimation asymptotics in conjunction with
Chirok Han, Jin Seo Cho, Peter C.B. Phillips   +2 more
core