Results 101 to 110 of about 11,858,600 (367)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The Difference in Lemuru Fish Oil Duration of Administration on Connective Tissue Fibroblast Cell Count in Rheumatoid Arthritis Rat Model

open access: yesJournal of Agromedicine and Medical Sciences (AMS), 2017
Rheumatoid arthritis is a joint chronic inflammation process leadingto progressive distruction.Cytokinessecreted from chronic inflammation increases fibroblast cell number that synthesize matrix metalloproteinase.
Asyirah Mujahidah Fillah   +2 more
doaj   +1 more source

The male to female ratio at birth in different regions in Malta [PDF]

open access: yes, 2015
Males are usually born in excess of females and the ratio of male births to female births is conventionally referred to as M/F. Many factors, including stress, privation and natural disasters are associated with a lowering of M/F. Malta has a North-South
Gatt, Miriam   +3 more
core  

Five‐Year Outcomes with PCI Guided by Fractional Flow Reserve

open access: yesNew England Journal of Medicine, 2018
BACKGROUND We hypothesized that fractional flow reserve (FFR)–guided percutaneous coronary intervention (PCI) would be superior to medical therapy as initial treatment in patients with stable coronary artery disease.
P. Xaplanteris   +25 more
semanticscholar   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Rolling-element fatigue life of AMS 5749 corrosion resistant, high temperature bearing steel [PDF]

open access: yes
The rolling element fatigue lives of AMS 5749 and AISI M-50 were compared in tests run in the five ball fatigue tester and the rolling contact fatigue tester.
Hodder, R. S., Parker, R. J.
core   +1 more source

Trefftz Difference Schemes on Irregular Stencils

open access: yes, 2009
The recently developed Flexible Local Approximation MEthod (FLAME) produces accurate difference schemes by replacing the usual Taylor expansion with Trefftz functions -- local solutions of the underlying differential equation.
Al Shenk   +50 more
core   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Stellar populations of classical and pseudo-bulges for a sample of isolated spiral galaxies

open access: yes, 2011
In this paper we present the stellar population synthesis results for a sample of 75 bulges in isolated spiral Sb-Sc galaxies, using the spectroscopic data from the Sloan Digital Sky Survey and the STARLIGHT code.
A. Durbala   +38 more
core   +1 more source

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