Results 141 to 150 of about 7,450,685 (340)
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin+14 more
wiley +1 more source
Consumption and nutrition: age - intake profiles for Czechoslovakia 1989 - 1992 [PDF]
This paper provides non-parametric estimates of the relation between nutrient intake and age for Czechoslovak individuals, as a function of characteristics of both the individual and the household she lives in, on the basis of household purchases ...
Laisney, François, Miquel, Ruth
core
Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park+6 more
wiley +1 more source
Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi+26 more
wiley +1 more source
biastest: Testing parameter equality across different models in Stata [PDF]
The biastest command in Stata is a powerful and user-friendly tool designed to compare the coefficients of different regression models, enabling researchers to assess the robustness and consistency of their empirical findings. This command is particularly valuable for evaluating alternative modeling approaches, such as ordinary least squares versus ...
arxiv
The male to female ratio at birth in different regions in Malta [PDF]
Males are usually born in excess of females and the ratio of male births to female births is conventionally referred to as M/F. Many factors, including stress, privation and natural disasters are associated with a lowering of M/F. Malta has a North-South
Gatt, Miriam+3 more
core
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam+9 more
wiley +1 more source
A Modified Pixel-Value Differencing Image Steganographic Scheme with Least Significant Bit Substitution Method [PDF]
Arun Malik+2 more
openalex +1 more source
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé+7 more
wiley +1 more source