Results 141 to 150 of about 2,977,856 (300)

Temporal Difference Learning in Complex Domains

, 1999
PhDThis thesis adapts and improves on the methods of TD(k) (Sutton 1988) that were successfully used for backgammon (Tesauro 1994) and applies them to other complex games that are less amenable to simple pattem-matching approaches.
Smith, Martin C.
core  

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Pengembangan Algoritma Kriptografi RSA-CRT dengan Teknik Steganografi Random Least Significant Bits (LSB)

, 2016
In this study the authors use Cryptographic Algorithms Rivest Shamir Adleman Chinese Remainder Theorem (RSA-CRT) and Steganography Technique Random Least Significant Bits (LSB).
Nasution, Nit Ravika
core  

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

A novel 1-channel EEG marker may associate with perioperative cognitive change. [PDF]

Front Syst Neurosci
Baron Shahaf D, Bolotin G, Cohen O, Raad M, Derman R, Shahaf G.   +5 more
europepmc   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Implementasi Least Significant Bit pada Citra Digital dengan Enkripsi Vigenère Cipher Berbasis Application Programming Interface

Steganografi adalah teknik untuk menyembunyikan informasi dalam citra digital, dan salah satu metode yang digunakan adalah LSB (Least Significant Bit).
Ade Lailani, Rohmi Dyah Astuti, vidia, vidia, Moh Arif Yahya, Yuliana   +4 more
core   +1 more source

A study to examine correlation between instructional leadership and teachers' motivation: evidence from TRNC. [PDF]

Front Psychol
Kalkan H, Acuner AM.
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Standard-Dose Ursodeoxycholic Acid Improves Biochemical Liver Function and Fibrosis in Chronic Liver Disease: Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial. [PDF]

J Korean Med Sci
Chang Y, Cho YK, Kim YS, Kim SE, Cheon GJ, Kim JH, Yang H, Kim W, Ahn SB, Yoon EL, Cheong JY, Lee JW, Kim MY, Kim HJ, Lee SH, Cho EY, Choi NR, Lee HW, Kim KM, Choe WH, Yu JM, Kim SY, Jang JY.   +22 more
europepmc   +1 more source