Results 71 to 80 of about 7,450,685 (340)

Spot‐14 and its paralog Spot‐14R regulate expression of metabolic and thermogenic pathway genes in murine brown and beige adipocytes

open access: yesFEBS Letters, EarlyView.
Spot‐14 and Spot‐14R play distinct roles in regulating metabolism in brown and beige adipocytes. While both influence lipid and glucose pathways, Spot‐14 uniquely controls thermogenic gene expression. This dual regulation balances energy storage and heat production, highlighting potential therapeutic targets for obesity and metabolic disorders. Spot 14
Lidia Itzel Castro‐Rodríguez   +3 more
wiley   +1 more source

Efficacy and safety of high flow nasal oxygen for children with bronchiolitis: systematic review and meta-analysis

open access: yesBMJ Open Respiratory Research, 2021
Background To assess the published evidence to establish the efficacy and safety of high flow oxygen cannula (HFNC) as respiratory support for children up to 24 months of age with bronchiolitis within acute hospital settings.Methods We searched eight ...
Sarah J Kotecha   +3 more
doaj   +1 more source

SIFT -- File Fragment Classification Without Metadata [PDF]

open access: yesarXiv, 2023
A vital issue of file carving in digital forensics is type classification of file fragments when the filesystem metadata is missing. Over the past decades, there have been several efforts for developing methods to classify file fragments. In this research, a novel sifting approach, named SIFT (Sifting File Types), is proposed.
arxiv  

Relação entre diferença mínima significativa e coeficiente de variação nos ensaios de competição de cultivares [PDF]

open access: yesCiência Rural, 1998
O objetivo deste trabalho foi caracterizar ensaios de competição de cultivares de milho, trigo, soja, feijão, cevada, aveia, triticale e sorgo conduzidos no Estado do Rio Grande do Sul e estimar a relação entre a diferença mínima significativa (DMS) e o coeficiente de variação (CV).
Lúcio, Alessandro Dal Col   +1 more
openaire   +4 more sources

Validating Variational Bayes Linear Regression Method With Multi-Central Datasets. [PDF]

open access: yes, 2018
PurposeTo validate the prediction accuracy of variational Bayes linear regression (VBLR) with two datasets external to the training dataset.MethodThe training dataset consisted of 7268 eyes of 4278 subjects from the University of Tokyo Hospital.
Asaoka, Ryo   +13 more
core   +1 more source

A cellular system to study responses to a collision between the transcription complex and a protein‐bound nick in the DNA template

open access: yesFEBS Letters, EarlyView.
We present the cellular transcription‐coupled Flp‐nick system allowing the introduction of a Top1‐mimicking cleavage complex (Flpcc) at a Flp recognition target site within a controllable LacZ gene. LacZ transcription leads to the collision of RNA polymerase II (RNAPII) with Flpcc, and this causes RNAPII stalling, ubiquitination, and degradation.
Petra Herring   +6 more
wiley   +1 more source

Subjectivity Problem in Student Assessment: Theoretical and Practical Aspects

open access: yesSocial Technologies, 2013
Objective evaluation is not an easy task when assessing student attainment even if we are evaluating such a well-measured subject as knowledge of mathematics. This subject is discussed in a number of papers.
Rima Kriauzienė   +2 more
doaj  

Racial and Ethnic Disparities in Influenza Vaccination among Adults with Chronic Medical Conditions Vary by Age in the United States. [PDF]

open access: yesPLoS ONE, 2017
People living with chronic health conditions exhibit higher risk for developing severe complications from influenza according to the Centers for Diseases Control and Prevention.
Degan Lu   +3 more
doaj   +1 more source

Optical Gravitational Lensing Experiment. OGLE-1999-BUL-32: the Longest Ever Microlensing Event -- Evidence for a Stellar Mass Black Hole? [PDF]

open access: yes, 2001
We describe the discovery of the longest microlensing event ever observed, OGLE-1999-BUL-32, also independently identified by the MACHO collaboration as MACHO-99-BLG-22. This unique event has an Einstein radius crossing time of 641 days. The high quality
Kubiak, M.   +8 more
core   +4 more sources

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

open access: yesFEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke   +2 more
wiley   +1 more source

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