Results 91 to 100 of about 544,201 (272)

Engineering Neuronal Network Connectivity Through Precise and Scalable Electrical Modulation

Advanced Science, EarlyView.
This study presents a scalable all‐electrical method for precise neuronal‐circuit reconfiguration based on high‐density microelectrode arrays. By employing biologically inspired plasticity rules, targeted connectivity changes were successfully induced and quantified across diverse neuronal preparations.
Sreedhar S. Kumar, Yannaël Bossard, Rachel Sava, Tobias Gänswein, Lorenca Sadiraj, Jean‐Samuel Dupré, Manuel Schröter, J. Gray Camp, Fernando Cardes, Julian Bartram, Andreas Hierlemann   +10 more
wiley   +1 more source

Natural Resistance to Ovarian Hyperstimulation Syndrome in Estrildid Finches Reveals Macrophage GPR183 as a Potential Therapeutic Target

Advanced Science, EarlyView.
Ovarian macrophage depletion reverses OHSS resistance in estrildid finches and exacerbates OHSS symptoms in rats. Activating macrophage GPR183 alleviates OHSS by reducing pro‐inflammatory factors, increasing immunomodulatory molecules, remodeling CD44/SDC4‐mediated communication, and restoring immune homeostasis.
Xiaofei Yan, Yongjie Huang, Jiabao Yang, Su Ma, Songsong Liu, Xuan Huang, Juergen Brosius, Huaping Zheng, Bing Yao, Li Chen, Shanshan Lai, Cheng Deng   +11 more
wiley   +1 more source

The least trimmed squares. Part I: Consistency.

Kybernetika, 2006
Consistency of the least trimmed squares is prooved in the framework with deterministic explanatory variables. Part II offers square-root consistency and Part III then Bahadur asymptotic representation.
openaire   +2 more sources

DMS‐MaPseq and DREEM Analyses Implicate the Critical Role of RNA Structural Dynamics in Turnip Yellow Mosaic Virus Pathogenicity

Advanced Science, EarlyView.
RNA structural profiling of Turnip Yellow Mosaic Virus by DMS‐MaPseq and DREEM analyses uncover that viral genome‐wide RSS is highly complicated and heterogeneous, with alternative RSSs widely distributed across the genome. Notably, the viral 3’ tRNA‐like structure adopts alternative conformations in vivo.
Jiaying Zhu, Changhao Li, Chisimbily Onyia, Xindi Li, Xingxing Yan, Songxiao Zhong, Taerin Oh, Xiuren Zhang   +7 more
wiley   +1 more source

Xenogeneic Mitochondrial Transplantation Improves Selected Age‐Associated Phenotypes in Mice

Advanced Science, EarlyView.
Yak‐derived xenogeneic mitochondrial transplantation improves selected age‐associated phenotypes in mice, enhances mitochondrial functional readouts, and engages host mitochondrial quality‐control pathways. Broad tissue biodistribution, increased ATP production and mtDNA copy number, reduced ROS levels and dysfunctional mitochondria, improved motility ...
Wenpeng Li, Xijia Wang, Yaning Hu, Zhen Yang, Tian Niu, Xingbo Zhao   +5 more
wiley   +1 more source

Price Transmission During Promotions: A Case Study of Spanish Milk Brands

Agribusiness, EarlyView.
ABSTRACT Price promotion is the marketing tool typically used by retail brands to boost sales and gain market share. In this paper, we intend to investigate the price transmission mechanism among competitive brands in Spain when price reductions that are associated with price promotions take place.
Yasmine Bedoui, Yan Jin, José María Gil   +2 more
wiley   +1 more source

Deep Learning Prediction of Surface Roughness in Multi‐Stage Microneedle Fabrication: A Long Short‐Term Memory‐Recurrent Neural Network Approach

Advanced Intelligent Discovery, EarlyView.
A sequential deep learning framework is developed to model surface roughness progression in multi‐stage microneedle fabrication. Using real‐world experimental data from 3D printing, molding, and casting stages, an long short‐term memory‐based recurrent neural network captures the cumulative influence of geometric parameters and intermediate outputs ...
Abdollah Ahmadpour, Sara Soltanabadi Farshi, Tuanna Ozcan, Amir Mohammad Ketabchi, Alper Kiraz, Savas Tasoglu   +5 more
wiley   +1 more source

Sampling Strategy: An Overlooked Factor Affecting Artificial Intelligence Prediction Accuracy of Peptides’ Physicochemical Properties

Advanced Intelligent Discovery, EarlyView.
This study reveals that sampling strategy (i.e., sampling size and approach) is a foundational prerequisite for building accurate and generalizable AI models in peptide discovery. Reaching a threshold of 7.5% of the total tetrapeptide sequence space was essential to ensure reliable predictions.
Meiru Yan, Ankeer Abuduhebaier, Haojin Zhou, Jiaqi Wang   +3 more
wiley   +1 more source

Data‐Driven Design of Bimodal Networked Dielectric Elastomers for High‐Performance Artificial Muscles

Advanced Intelligent Systems, EarlyView.
A data‐efficient artificial intelligence‐assisted framework, which integrates experimental data with machine learning, is developed for the design of bimodal networked dielectric elastomers (DEs) as advanced artificial muscles. It adopts neural networks to predict DEs’ mechanical properties and support vector machines to classify electromechanical ...
Ofoq Normahmedov, Hanzhi Ma, Junbo Peng, Huifeng Dong, Jiangshan Zhuo, Mengke Shi, Lvting Wang, Shengchao Jiang, Ye Shi   +8 more
wiley   +1 more source

Optimizing 3D Bin Packing of Heterogeneous Objects Using Continuous Transformations in SE(3)

Advanced Intelligent Systems, EarlyView.
This article presents a method for solving the three‐dimensional bin packing problem for heterogeneous objects using continuous rigid‐body transformations in SE(3). A heuristic optimization framework combines signed‐distance functions, neural network approximations, point‐cloud bin modeling, and physics simulation to ensure feasibility and stability ...
Michele Angelini, Marco Carricato
wiley   +1 more source