Results 41 to 50 of about 36,978 (336)

Reduced Lecithin [PDF]

Clinical Cancer Research, 2004
Abstract Purpose: Retinoids, which include vitamin A (retinol; ROL) and its derivatives, have been investigated in the treatment of bladder cancer. We have shown that expression of the enzyme lecithin:ROL acyltransferase (LRAT), which converts ROL to retinyl esters, is reduced in several human cancers.
Stephen Boorjian, Satish K. Tickoo, Nigel P. Mongan, Huayin Yu, Dean Bok, Robert R. Rando, David M. Nanus, Douglas S. Scherr, Lorraine J. Gudas   +8 more
openaire   +1 more source

Morphological and Physical Analysis of Natural Phospholipids-Based Biomembranes [PDF]

, 2014
Background: Liposomes are currently an important part of biological, pharmaceutical, medical and nutritional research, as they are considered to be among the most effective carriers for the introduction of various types of bioactive agents into target ...
Arab-Tehrany, Elmira, Dehghani, Fariba, Francius, Grégory, Jacquot, Adrien, Linder, Michel, Razafitianamaharavo, Angelina, Tamayol, Ali   +6 more
core   +4 more sources

Effect of phospholipids and bile acids on cholesterol nucleation time and vesicular/micellar cholesterol in gallbladder bile of patients with cholesterol stones [PDF]

, 1993
Supersaturation and rapid nucleation of cholesterol in bile are of key importance in the pathogenesis of cholesterol gallstones. While the effects of bile acids and phospholipids on cholesterol saturation of bile have been extensively studied, their ...
Huber, P., Jüngst, Dieter, Lang, Thomas, Lange, V., Paumgartner, Gustav   +4 more
core  

The influence of anesthetics, neurotransmitters and antibiotics on the relaxation processes in lipid membranes [PDF]

, 2007
In the proximity of melting transitions of artificial and biological membranes fluctuations in enthalpy, area, volume and concentration are enhanced. This results in domain formation, changes of the elastic constants, changes in permeability and slowing ...
Antonov V. F., Antonov V. F., Blume A., Bovill J. G., Brown D. A., Böckmann R. A., Böttner M., Cannon B., Cantor R. S., Cantor R. S., Cantor R. S., Chapman D., Cruzeiro-Hansson L., Ebel H., Ebel H., Elamrani K., Franks N., Gaus K., Gennis R. B., Genz A., Grabitz P., Gruenewald B., Halstenberg S., Halstenberg S., Heimburg T., Heimburg T., Heimburg T., Heimburg T., Heimburg T., Helms J. B., Hill T. L., Hinderliter A., Hinz H.-J., Holzwarth J. F., Holzwarth J. F., Jackson M. B., Jacobson K., Johnson M. L., Kaufmann K., Kharakoz D. P., Korlach J., Krasowski M., Lee J., Melchior D. L., Melo E. C., Mitaku S., Mountcastle D., Nagle J. F., Onsager L., Onsager L., Papahadjopoulos D., Pollakowski D., Sackmann E., Salinas D. G., Schmidt D., Seeger H., Seeger H. M., Seeger H. M., Simons K., Singer S., Steim J. M., Strehlow U., Tamura K., Thompson T., Trudell J. R., Träuble H., Tsong T. Y., Tsong T. Y., Turnheim K., Ueda I., van Osdol W. W., van Osdol W. W., van Osdol W. W., van Osdol W. W., Vaz W. L., Winter R., Yao H.   +76 more
core   +2 more sources

Liquid Crystalline Inverted Lipid Phases and Reverse Micelles in Drug Delivery: From Molecular Design to Therapeutic Potential

Advanced Functional Materials, EarlyView.
Liquid crystalline inverted lipid phases and reverse micelles are self‐assembled lipid nanostructures that enhance the solubility, stability, and delivery of diverse therapeutics. This review integrates their physicochemical principles, formulation strategies, drug loading mechanisms, and biomedical applications, highlighting their growing ...
Numan Eczacioglu, Mulazim Hussain Asim, Soheil Haddadzadegan, Andreas Bernkop‐Schnürch   +3 more
wiley   +1 more source

Fractionation of naturally occurring lecithins according to degree of unsaturation by thin-layer chromatography

Journal of Lipid Research, 1965
Intact, naturally occurring lecithins were fractionated according to degree of unsaturation by thin-layer chromatography on silica gel plates impregnated with silver nitrate and heated at 175–180° for several hours.
Gösta A.E. Arvidson
doaj   +1 more source

Membrane proteins and proteomics: Love is possible, but so difficult [PDF]

, 2009
Despite decades of extensive research, the large-scale analysis of membrane proteins remains a difficult task. This is due to the fact that membrane proteins require a carefully balanced hydrophilic and lipophilic environment, which optimum varies with ...
Adessi, Aebersold, Aivaliotis, Aivaliotis, Alla, Ames, Babu, Bagshaw, Bell, Berlanda-Scorza, Berven, Bierczynska-Krzysik, Bisle, Bjellqvist, Bunai, Bunai, Burré, Buxbaum, Casey, Chevallet, Chevallet, Connolly, Coughenour, Cutillas, Devreese, Eravci, Everberg, Felsted, Ferro, Gatlin, Ghosh, Gyenes, Görg, Hagan, Hahne, Hartinger, Helling, Henningsen, Henzel, Hisabori, Hjelmeland, Huang, Huang, James, Jun, Lasonder, Lescuyer, Liberatori, Lopez, Low, Luche, Lyubimova, Lüddens, MacFarlane, MacFarlane, Matsudaira, McDonough, Miguet, Moebius, Molloy, Molloy, Nandakumar, Natera, Navarre, Ong, Papasotiriou, Pappin, Patton, Pedersen, Peng, Perdew, Phadke, Rabilloud, Rabilloud, Rabilloud, Rabilloud, Rabilloud, Rais, Rubin, Santoni, Santoni, Schindler, Schirle, Schägger, Siroy, Speers, Sweetnam, Switzer, Tastet, Taylor, Towbin, Veith, Washburn, Werner, Wilkins, Williams, Williams, Williams, Wittig, Witzmann, Wu, Yates, Ying, Zahedi   +103 more
core   +5 more sources

Emulsifying Properties of Different Modified Sunflower Lecithins

, 2012
Lecithins are a mixture of acetone-insoluble phospholipids and other minor substances (triglycerides, carbohydrates, etc.). The most commonly processes used for lecithin modification are: fractionation by deoiling to separate oil from phospholipids ...
D. Cabezas, R. Madoery, B. W. Diehl, M. Tomás   +3 more
semanticscholar   +1 more source

Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs

Advanced Healthcare Materials, EarlyView.
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner, Stefan Keim, Soheil Haddadzadegan, Odile Fernandez Romero, Katrin Zöller, Gabriel Stern, Ilaria Cesi, Krum Kafedjiiski, Andreas Bernkop‐Schnürch   +8 more
wiley   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source