Results 11 to 20 of about 209,739 (264)

Lectins with Potential for Anti-Cancer Therapy

open access: yesMolecules, 2015
This article reviews lectins of animal and plant origin that induce apoptosis and autophagy of cancer cells and hence possess the potential of being developed into anticancer drugs. Apoptosis-inducing lectins encompass galectins, C-type lectins, annexins,
Tammy Yau   +3 more
doaj   +1 more source

Alginate Modification and Lectin-Conjugation Approach to Synthesize the Mucoadhesive Matrix

open access: yesApplied Sciences, 2021
Alginates are natural anionic polyelectrolytes investigated in various biomedical applications, such as drug delivery, tissue engineering, and 3D bioprinting. Functionalization of alginates is one possible way to provide a broad range of requirements for
Arlina Prima Putri   +3 more
doaj   +1 more source

Lectin microarray [PDF]

open access: yesPROTEOMICS – Clinical Applications, 2009
AbstractLectin microarray is a new technology that utilizes a panel of lectins immobilized on well‐defined substrate for high‐throughout analysis of glycans and glycoproteins. In this article, we have reviewed the fabrication and detection schemes in lectin microarray and discussed its novel applications in glycomics. We have also demonstrated a lectin
Shen, Hu, David T, Wong
openaire   +2 more sources

Synthesis of β-d-galactopyranoside-Presenting Glycoclusters, Investigation of Their Interactions with Pseudomonas aeruginosa Lectin A (PA-IL) and Evaluation of Their Anti-Adhesion Potential

open access: yesBiomolecules, 2019
Pseudomonas aeruginosa is an opportunistic human pathogen associated with cystic fibrosis. This bacterium produces, among other virulence factors, a soluble d-galactose-specific lectin PA-IL (LecA).
Lenka Malinovská   +10 more
doaj   +1 more source

Purification, Characterization and Antioxidant Potential of a Novel Lectin from Pterocarpus soyauxii Taub Seeds

open access: yesNotulae Scientia Biologicae, 2019
The study investigated the presence of lectin in the seeds of Pterocarpus soyauxii, purified the lectin and determined its physicochemical properties as well as its antioxidant potential. Purification of P.
Oludele Olayemi ODEKANYIN   +2 more
doaj   +1 more source

An algal lectin griffithsin inhibits Hantaan virus infection in vitro and in vivo

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
Hantaan virus (HTNV) is the etiological pathogen of hemorrhagic fever with renal syndrome in East Asia. There are currently no effective therapeutics approved for HTNV and other hantavirus infections.
Yajing Zhao   +25 more
doaj   +1 more source

Separation and Enrichment of Lectin from Zihua Snap-Bean (Phaseolus vulgaris) Seeds by PEG 600–Ammonium Sulfate Aqueous Two-Phase System

open access: yesMolecules, 2017
A fast and efficient method based on a polyethylene glycol (PEG) 600/(NH4)2SO4 aqueous two-phase system for extracting lectin from Zihua snap-bean (Phaseolus vulgaris) seeds was established. According to a Box–Behnken design (BBD), involving four factors
Bin Jiang   +4 more
doaj   +1 more source

Identification of Echinacea Purpurea (L.) Moench Root LysM Lectin with Nephrotoxic Properties

open access: yesToxins, 2020
Echinacea purpurea (L.) Moench (EP) is a well-studied plant used for health benefits. Even though there are a lot of data on EP secondary metabolites, its active proteins are not studied well enough.
Gabriele Balciunaite   +7 more
doaj   +1 more source

Supramolecular Binding with Lectins: A New Route for Non-Covalent Functionalization of Polysaccharide Matrices

open access: yesMolecules, 2022
The chemical functionalization of polysaccharides to obtain functional materials has been of great interest in the last decades. This traditional synthetic approach has drawbacks, such as changing the crystallinity of the material or altering its ...
Devis Montroni   +3 more
doaj   +1 more source

Lectins, lectin genes, and their role in plant defense. [PDF]

open access: yesThe Plant Cell, 1991
Lectins are carbohydrate-binding proteins that bind gly? cans of glycoproteins, glycolipids, or polysaccharides with high affinity (Goldstein and Hayes, 1978). Because of their binding specificity, they have the capability to serve as recognition molecules within a cell, between cells, or be? tween organisms. It is assumed that lectins play fundamental
M J, Chrispeels, N V, Raikhel
openaire   +2 more sources

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