Results 71 to 80 of about 327,566 (304)

Mechanically Spatio‐Chimeric Fibrin Assembly Enables Vascular‐Integrated Muscle Reconstruction for Volumetric Muscle Loss Repair

Advanced Materials, EarlyView.
SPARC (spatio‐chimeric, plasma‐based, anisotropic, and shear‐responsive construct) that integrates myogenic and vascular microenvironments within a single construct. The dual‐modulus matrix directs aligned myotube formation and endothelial network development, enabling a vascularized muscle implant that seamlessly anastomoses with host tissue and ...
Su Hyun Jung, Minjun Kim, Da‐Yoon Kim, Min Kyu Kim, Sieun Lee, Yoonhee Jin, Joo H. Kang   +6 more
wiley   +1 more source

Use of Aleuria alantia Lectin Affinity Chromatography to Enrich Candidate Biomarkers from the Urine of Patients with Bladder Cancer

Proteomes, 2015
Developing a urine test to detect bladder tumours with high sensitivity and specificity is a key goal in bladder cancer research. We hypothesised that bladder cancer-specific glycoproteins might fulfill this role.
Sarah R. Ambrose, Naheema S. Gordon, James C. Goldsmith, Wenbin Wei, Maurice P. Zeegers, Nicholas D. James, Margaret A. Knowles, Richard T. Bryan, Douglas G. Ward   +8 more
doaj   +1 more source

Carbohydrate-binding protein from stinging nettle as fusion inhibitor for SARS-CoV-2 variants of concern

Frontiers in Cellular and Infection Microbiology, 2022
Urtica dioica agglutinin (UDA) is a carbohydrate-binding small monomeric protein isolated from stinging nettle rhizomes. It inhibits replication of a broad range of viruses, including coronaviruses, in multiple cell types, with appealing selectivity.
Emiel Vanhulle, Thomas D’huys, Becky Provinciael, Joren Stroobants, Anita Camps, Sam Noppen, Dominique Schols, Els J. M. Van Damme, Piet Maes, Annelies Stevaert, Kurt Vermeire   +10 more
doaj   +1 more source

Unlocking the Potential of MXene‐Based Electrochemical Biosensors: A Review of Biofunctionalization Strategies and Biosensing Principles

Advanced Materials Technologies, EarlyView.
ABSTRACT Electrochemical biosensors enable the accurate and timely detection of clinical biomarkers, improving healthcare and precision medicine. MXene nanosheets, a class of 2D transition metal carbides, nitrides, and carbonitrides, are promising materials for developing next‐generation electrochemical biosensors due to their unique physicochemical ...
Muhsin Ali, Sharat Chandra Barman, Isobel Steer, Aya H. Alshareef, Dana Alsulaiman   +4 more
wiley   +1 more source

Cancer targeting with biomolecules: a comparative study of photodynamic therapy efficacy using antibody or lectin conjugated phthalocyanine-PEG gold nanoparticles [PDF]

, 2015
The functionalisation of therapeutic nanoparticle constructs with cancer-specific biomolecules can enable selective tumour accumulation and targeted treatment. Water soluble gold nanoparticles (ca.
Allen, Arap, Bechet, Bertrand, Boya, Bullous, David A. Russell, Davis, Dougherty, Gary-Bobo, Girgis Obaid, Hamblin, Harris, Hogemann-Savellano, Hone, Isabelle Chambrier, Iversen, Jeyaprakash, Jin, Kim, Konska, Kopeček, Lindig, Marín, Mew, Michael J. Cook, Obaid, Oleinick, Orlova, Poiroux, Qualls, Robertson, Ross, Schafer, Schrama, Slamon, Spring, Springer, Stuchinskaya, Sudimack, Tang, Vacha, Wang, Weissenbock, Wieder, Xu, Yarden, Yu, Yu, Zhang   +49 more
core   +1 more source

Engineered Mesenchymal Stem Cell–NK Cell Complexes for Spatially Targeted and Functionally Revitalized Cancer Immunotherapy

Advanced Science, EarlyView.
IL‐15‐engineered stem cell–NK cell complexes, assembled via bioorthogonal chemistry, enable effective lung cancer immunotherapy. Abstract Natural killer (NK) cells represent a powerful immunotherapeutic strategy due to their intrinsic cytotoxicity and ability to target tumor cells independently of antigen presentation.
Qian Zhang, Bo Yin, Munaiwaier Sabier, Youlan Yang, Mengling Wu, Zhouping Zhao, Xuanzhi Luo, Yuehong Zhong, Xiuming Zhu, Jie Zhang, Jing Wang, Kai Chen, Fei Ruan, Wei Zhang, Zhimin Lu, Jiong Wang   +15 more
wiley   +1 more source

Immunomodulatory Effects of Edible and Medicinal Mushrooms and Their Bioactive Immunoregulatory Products

Journal of Fungi, 2020
Mushrooms have been valued as food and health supplements by humans for centuries. They are rich in dietary fiber, essential amino acids, minerals, and many bioactive compounds, especially those related to human immune system functions. Mushrooms contain
Shuang Zhao, Qi Gao, Chengbo Rong, Shouxian Wang, Zhekun Zhao, Yu Liu, Jianping Xu   +6 more
doaj   +1 more source

Glycotope structures and intramolecular affinity factors of plant lectins for Tn/T antigens [PDF]

, 2011
B
A Babino, AA Jeyaprakash, AM Wu, AM Wu, AM Wu, AM Wu, AM Wu, AM Wu, AM Wu, AM Wu, E Zenteno, EJM Damme Van, GF Springer, GF Springer, GF Springer, GWG Bird, K Puri, KA Kulkarni, KA Kulkarni, M Duk, M Duk, M Sarkar, N Taniguchi, N Vega, R Lotan, R Ravishankar, R Sankaranarayanan, R Zenteno, S Hirohashi, S Tollefsen, SH Itzkowitz, SI Hakomori, SI Hakomori, SI Hakomori, SJ Rinderle, T Singh, T Singh, T Singh, TR Transue, V Piller, W Wang, X Lee, Y Yoda   +42 more
core   +3 more sources

rWTC‐MBTA Vaccine, Alone and Enhanced with Anti‐PD1, Elicits Immune Responses against CNS and Peripheral B‐Cell Lymphoma

Advanced Science, EarlyView.
An autologous whole‐tumor‐cell vaccine (rWTC‐MBTA) is evaluated in murine CNS lymphoma. Subcutaneous vaccination activates dendritic cells, broadens T‐cell priming, and drives lymphocyte trafficking to brain tumors, producing durable tumor control. Longitudinal bioluminescence and adoptive‐transfer assays verify CNS engagement. Combination with anti‐PD‐
Yaping Zhang, Juan Ye, Mitchell Sun, Samik Chakraborty, Alex Valenzuela, Shuran Chen, Qingfeng Xue, Wenyu Shi, Karel Pacak, Herui Wang, Zhengping Zhuang   +10 more
wiley   +1 more source

Natural lectin activity in the haemolymph of Panstrogylus megistus (Heteroptera: Reduvidae) Atividade lectínica na hemolinfa de Panstrongylus megistus (Heteroptera: Reduviidae)

Memorias do Instituto Oswaldo Cruz, 1988
The haemolymph of Panstrongylus megistus showed a natural lectin activity for a wide range of vertebrate erythocytes. Agglutination was observed against all vertebrate erythrocytes tested (human ABO, duck, rabbit, mouse, sheep, chicken and cow).
Y. M. Gomes, A. F. Furtado, A. B. de Carvalho   +2 more
doaj   +1 more source