Results 121 to 130 of about 161,997 (297)

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

LED and LED Lighting

The Journal of The Institute of Image Information and Television Engineers, 2012
openaire   +2 more sources

Klinischer Langzeiterfolg der Nanohybridkomposite Grandio® und Filtek™ Supremé in Klasse I und II Kavitäten in Abhängigkeit von dem verwendeten Lichthärtegerät (Halogen oder LED) [PDF]

, 2017
Torsten Pflaum
openalex  

Community-Led, Cross-Sector Partnership of Housing and Health Care to Promote Aging in Place (Unite Health Project): Protocol for a Prospective Observational Study [PDF]

, 2023
Lesli E. Skolarus, Erica Thrash-Sall, Abby Katherine Hellem, Michael Giacalone, James Burke, Chun Chieh Lin, Sarah Bailey, Casey L. Corches, Mackenzie Dinh, Amanda Casetti, Maria Mansour, Kaitlyn Bowie, Rylyn Roth, Candace Whitfield, Anne Sales   +14 more
openalex   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

OCC-Based Positioning Method for Autonomous UAV Navigation in GNSS-Denied Environments: An Offshore Wind Farm Simulation Study. [PDF]

Sensors (Basel)
Kim JH, Jung SY.
europepmc   +1 more source

AlGaInP LED with low-speed spin-coating silver nanowires as transparent conductive layer [PDF]

, 2014
Xia Guo, Chun Wei Guo, Cheng Wang, Chong Li, Xiao Ming Sun   +4 more
openalex   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Investigation of a PID-Based Dynamic Illuminance Control System for Intelligent Neonatal Jaundice Phototherapy Using a Blue Light LED Array. [PDF]

Sensors (Basel)
Xie M, Zheng H, Liu M, Wen X, Fan Y, Lu BY.   +5 more
europepmc   +1 more source