Results 161 to 170 of about 87,522 (313)

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Difunctionalization of unsaturated hydrocarbons via EDA complexes to access pentafluorosulfanyl thioethers. [PDF]

Nat Commun
Zhang X, Jiang Y, Yang HY, Ma Y, Zhang J, Zhang N, Wu G, Sun D, Shi Y, Zhang W, Yue S, Guo S, Wang J.   +12 more
europepmc   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Eye Safety of Light-Emitting Diodes in Toys: The Results of Three Years of Market Surveillance. [PDF]

Int J Environ Res Public Health
Attia D, Enouf O, Behar-Cohen F, Martinsons C.   +3 more
europepmc   +1 more source

倒装结构大功率蓝光LEDs的研制

, 2006
从器件制作角度入手，对基于Ⅲ族氮化物的功率型蓝光LEDs结构和电极体系进行了优化设计。采用梳状结构、高反电极体系及倒装焊技术，研制出大功率蓝光LEDs，在350mA工作电流下，工作电压为3．3～3．5V，输出功率达137．71mW ...
郭金霞, 伊晓燕, 刘志强, 王立彬, 陈宇, 王良臣, 马龙   +6 more
core  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Ageing Analysis of Light-Emitting Diodes Used in Consumer Lighting. [PDF]

Materials (Basel)
Ludvig LÁ, Forczek B, Harsányi G.
europepmc   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Nitride-Based Quantum Structures in Optoelectronics-A Survey of Colors. [PDF]

Materials (Basel)
Gorczyca I, Suski T, Perlin P, Staszczak G.   +3 more
europepmc   +1 more source