Results 51 to 60 of about 148,554 (285)

The Moonshine Module for Conway's Group [PDF]

open access: yes, 2014
We exhibit an action of Conway's group---the automorphism group of the Leech lattice---on a distinguished super vertex operator algebra, and we prove that the associated graded trace functions are normalized principal moduli, all having vanishing ...
Duncan, John F. R., Mack-Crane, Sander
core  

Encoding of Tactile Stimuli by Mechanoreceptors and Interneurons of the Medicinal Leech [PDF]

open access: yes, 2016
For many animals processing of tactile information is a crucial task in behavioral contexts like exploration, foraging, and stimulus avoidance. The leech, having infrequent access to food, developed an energy efficient reaction to tactile stimuli ...
Fathiazar, Elham   +3 more
core   +4 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Treatment of cutaneous leishmaniasis lesion caused by Leishmania major using leech therapy in BALB/c mice

open access: yesJournal of Vector Borne Diseases
Background & objectives: Amphotericin B, Allopurinol, Glucantime and Beta-Glucan are the main drugs currently used for the treatment of cutaneous leishmaniasis.
Leila Shirani-Bidabadi
doaj   +1 more source

Neuronal Control of Swimming Behavior: Comparison of Vertebrate and Invertebrate Model Systems [PDF]

open access: yes, 2011
Swimming movements in the leech and lamprey are highly analogous, and lack homology. Thus, similarities in mechanisms must arise from convergent evolution rather than from common ancestry.
Buchanan, James T.   +3 more
core   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Development of a mitochondrial mini-barcode and its application in metabarcoding for identification of leech in traditional Chinese medicine

open access: yesScientific Reports
In Traditional Chinese Medicine (TCM), the medicinal leech is vital for treatments to promote blood circulation and eliminate blood stasis. However, the prevalence of counterfeit leech products in the market undermines the quality and efficacy of these ...
Chenfeng Shi   +5 more
doaj   +1 more source

The complete mitochondrial genome of Hemiclepsis yangtzenensis (Clitellata: Glossiphoniidae)

open access: yesMitochondrial DNA. Part B. Resources, 2022
We present the complete mitochondrial genome sequence of a recently described new leech species named Hemiclepsis yangtzenensis Yang & Bolotov 2021 collected in central China.
Ti-Lin Yi   +3 more
doaj   +1 more source

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