Results 31 to 40 of about 5,649,672 (258)

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams   +8 more
wiley   +1 more source

Analysis of the asymmetrically expressed Ablim1 locus reveals existence of a lateral plate Nodal-independent left sided signal and an early, left-right independent role for nodal flow.

, 2010
BACKGROUND: Vertebrates show clear asymmetry in left-right (L-R) patterning of their organs and associated vasculature. During mammalian development a cilia driven leftwards flow of liquid leads to the left-sided expression of Nodal, which in turn ...
Norris, Dominic P., Peter Underhill, Norris, DP, Hilton, Helen, Alexander Ermakov, Bhattacharya, S, Underhill, P, Brown, NA, Dominic P Norris, Underhill, Peter, Hilton, H, Stevens, Jonathan, Bragança, José, Jonathan Stevens, Shoumo Bhattacharya, Ermakov, A, Braganca, J, Bhattacharya, Shoumo, Jose Braganca, Nigel A Brown, Stevens, J, Brown, Nigel A., Helen Hilton, Ermakov, Alexander   +23 more
core   +1 more source

Los estereotipos arraigados en la lengua: el concepto de derecho e izquierdo en español y polaco

Studia Iberystyczne, 2012
STEREOTYPES FOUND IN A LANGUAGE: THE CONCEPT OF RIGHT AND LEFT IN SPANISH AND POLISH This article focuses on the comparative analysis of the concepts of right and left in Spanish and Polish.
Cecylia Tatoj
doaj   +1 more source

Development and Validation of R-hf Risk Score in Acute Heart Failure Patients in the Middle East

Oman Medical Journal, 2023
Objectives: The Rajan’s heart failure (R-hf) score was proposed to aid risk stratification in heart failure patients. The aim of this study was to validate R-hf risk score in patients with acute decompensated heart failure.
Rajesh Rajan, Mohammed Al Jarallah, Ibrahim Al-Zakwani, Raja Dashti, Kadhim Sulaiman, Prashanth Panduranga, Peter A Brady, Zhanna Kobalava   +7 more
doaj   +1 more source

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman, Katherine K. Matthay, Fabienne Hollinger, Catriona Black, Ann A. Lazar, Miguel Pampaloni, Steven G. DuBois, Kieuhoa T. Vo   +7 more
wiley   +1 more source

Hospitalization Through Families’ Eyes: Comparing Inpatient Care Quality for Children With Sickle Cell Disease and Cystic Fibrosis in Canada

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker, Kyle Kemp, Perri Tutelman, Sharon H. J. Hou, Paul Fairie, Maria Santana, Gregory M. T. Guilcher, Taryn Fay‐McClymont, Glenda Bendiak, Wendy Pelletier, Nicola Wright, Fiona Schulte   +11 more
wiley   +1 more source

Venous Thromboembolism in Pediatric Bone Sarcoma Patients: A 10‐Year, Single‐Institution Experience Encompassing the COVID‐19 Pandemic

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Osteosarcoma (OS) and Ewing sarcoma (EWS) are the most common primary bone cancers in children, but acute thrombosis is poorly characterized in this population. Our study evaluated the rates of venous thromboembolism (VTE) and associated risk factors in pediatric patients with bone sarcomas treated over a 10‐year period encompassing
Sarah Kappa, Shou Xu, Mark Zobeck, Sarah E. Sartain, Nino Rainusso, Lisa Wang, Nicole Montgomery, Paige Wheaton, Sarah Whittle   +8 more
wiley   +1 more source

Structural Elucidation, Antioxidant Properties, and In Silico Molecular Docking of Schiff Base Complexes Derived from Naphthalene-1,8-diamine and Terephthalaldehyde

Indonesian Journal of Chemistry
By combining two mmol of naphthalene-1,8-diamine with one mmol of terephthalaldehyde, a TPAL-DAN ligand was synthesized. Six metal salts: Mn(II), Co(II), Ni(II), Cu(II), Zn(II), and Cd(II) were used to prepare six Schiff base complexes.
Chanar Ahmed Hussein, Khansaa Shakir Al-Nama, Ammar Abdulsattar Ibrahim   +2 more
doaj   +1 more source

Restauración neo-conservadora y crisis de las izquierdas latinoamericanas: reflexiones desde las culturas políticas [PDF]

Aposta, 2020
El objetivo del presente artículo es analizar la situación actual de la política representativa en América Latina, en el marco del proceso de restauración de partidos y/o coaliciones pertenecientes a la derecha política, tomando en consideración cambios ...
Francisco Iván Sotomayor López
doaj  

Serological Benefit of SARS‐CoV‐2 Vaccination Relative to Infection in Children With Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro, Freda Qi, Karen Colwill, Alina D. Dorogy, Ying Liu, Michelle Science, Anne‐Claude Gingras, James M. Rini, Sumit Gupta, Sarah Alexander, Shelly Bolotin, Tania H. Watts   +11 more
wiley   +1 more source