Results 171 to 180 of about 23,249 (261)

Prospective in silico trials identify combined SK and K2P channel block as an effective strategy for atrial fibrillation cardioversion

The Journal of Physiology, EarlyView.
Abstract figure legend In silico trials were conducted in 654 virtual patients with atrial fibrillation (AF) to assess the cardioversion efficacy of three pharmacological treatments: single SK and K2P channel block and combined SK+K2P channel inhibition. Left: representative virtual AF patient with the atria inside the torso.
Albert Dasí, Lucas Arantes Berg, Hector Martinez‐Navarro, Alfonso Bueno‐Orovio, Blanca Rodriguez   +4 more
wiley   +1 more source

Giant Isolated Congenital Left Atrial Appendage Aneurysm Complicated by Thrombus: Multimodality Imaging Assessment. [PDF]

JACC Case Rep
Alanís-Naranjo JM, Meléndez-Ramírez G, de la Mora-Cervantes R, Arias-Godínez JA, Meave-González A, Jiménez-Becerra S, Patrón-Chi SA.   +6 more
europepmc   +1 more source

Advances in cardiac devices and bioelectronics augmented with artificial intelligence

The Journal of Physiology, EarlyView.
Abstract figure legend Interfaces between the human heart, diagnostic bioelectronics, artificial intelligence, and clinical care. From left to right: Human heart and biosensor interface; representative waveforms of common diagnostic bioelectronic sensing modalities.
Charles Stark, Eric Rytkin, Andrei Alexandru Mircea, Igor R. Efimov   +3 more
wiley   +1 more source

Congenital left atrial appendage aneurysm in an adolescent: Diagnostic clues and surgical management. [PDF]

JTCVS Tech
Huang Y, Ahmad N, Chen X, Huang L.
europepmc   +1 more source

Cardiac remodelling in type 2 diabetes: Pathophysiological mechanisms and opportunities for multiscale computational modelling and simulation

The Journal of Physiology, EarlyView.
Abstract figure legend Overview of multiscale cardiac remodelling in type 2 diabetes and how to model and simulate these changes using a human‐based, multiscale computational framework. Cardiac remodelling in type 2 diabetes occurs at ionic channel, protein, cellular, tissue and whole‐organ level, affecting the electrophysiological function, mechanical
Ambre Bertrand, Jakub Tomek, Blanca Rodriguez   +2 more
wiley   +1 more source

Bigger May Be Better Indeed?: Navigating Device Sizing in Left Atrial Appendage Closure. [PDF]

JACC Asia
Ko AHY, Wong I.
europepmc   +1 more source

Enhancing stroke risk stratification in atrial fibrillation through non‐Newtonian blood modelling and Gaussian process emulation

The Journal of Physiology, EarlyView.
Abstract figure legend Non‐Newtonian modelling and GPEs for stroke risk in atrial fibrilation patients. Abstract Atrial fibrillation (AF) is the most common heart arrhythmia, linked to a five‐fold increase in stroke risk. The left atrial appendage (LAA), prone to blood stasis, is a common thrombus formation site in AF patients.
Paolo Melidoro, Abdel Rahman Amr Sultan, Ahmed Qureshi, Magdi H. Yacoub, Khalil L. Elkhodary, Gregory Y. H. Lip, Natalie Montarello, Nishant Lahoti, Ronak Rajani, Magdalena Klis, Steven E. Williams, Oleg Aslanidi, Adelaide De Vecchi   +12 more
wiley   +1 more source

MAUDE Registry Analysis of Pericardial Effusions Following Watchman and Amulet Left Atrial Appendage Occlusion. [PDF]

JACC Adv
Limaye SS, Schwarz KQ, Aktas MK, Ling FS.   +3 more
europepmc   +1 more source

Defying gravity: Breath, beat and brain

Experimental Physiology, EarlyView.
Shigehiko Ogoh, Damian Miles Bailey
wiley   +1 more source

Senolytics and exercise: Dual modalities for rejuvenating muscle

The Journal of Physiology, EarlyView.
Abstract figure legend The role of senolytics on the heart and skeletal muscle. Senescent cell burden increases with ageing, disuse and disease. The senolytics dasatinib+quercetin (D+Q), navitoclax and fisetin, as well as exercise, eliminate senescent cells, reducing senescent cell burden and their senescence‐associated secretory phenotype (SASP ...
Zeynep Elif Yesilyurt‐Dirican, Ce Qi, Uchenna Okpechi, Maya Strand Ford, Georgina M. Ellison‐Hughes   +4 more
wiley   +1 more source