Results 221 to 230 of about 39,962 (306)

Cardiac remodelling in type 2 diabetes: Pathophysiological mechanisms and opportunities for multiscale computational modelling and simulation

The Journal of Physiology, EarlyView.
Abstract figure legend Overview of multiscale cardiac remodelling in type 2 diabetes and how to model and simulate these changes using a human‐based, multiscale computational framework. Cardiac remodelling in type 2 diabetes occurs at ionic channel, protein, cellular, tissue and whole‐organ level, affecting the electrophysiological function, mechanical
Ambre Bertrand, Jakub Tomek, Blanca Rodriguez   +2 more
wiley   +1 more source

Percutaneous Left Atrial Appendage Closure: Current Evidence and Procedural Insights. [PDF]

Rev Cardiovasc Med
Mohandes M, Shihadeh LA, Pernigotti A, Torres M, Moreno C, Bejarano R, Fernández F, Guarinos J, Ferreiro JL.   +8 more
europepmc   +1 more source

Enhancing stroke risk stratification in atrial fibrillation through non‐Newtonian blood modelling and Gaussian process emulation

The Journal of Physiology, EarlyView.
Abstract figure legend Non‐Newtonian modelling and GPEs for stroke risk in atrial fibrilation patients. Abstract Atrial fibrillation (AF) is the most common heart arrhythmia, linked to a five‐fold increase in stroke risk. The left atrial appendage (LAA), prone to blood stasis, is a common thrombus formation site in AF patients.
Paolo Melidoro, Abdel Rahman Amr Sultan, Ahmed Qureshi, Magdi H. Yacoub, Khalil L. Elkhodary, Gregory Y. H. Lip, Natalie Montarello, Nishant Lahoti, Ronak Rajani, Magdalena Klis, Steven E. Williams, Oleg Aslanidi, Adelaide De Vecchi   +12 more
wiley   +1 more source

The clinical association of left atrial appendage thrombus on CTA with functional outcome. [PDF]

Eur Stroke J
Winders J, Di Bartolo A, Kim J, Wilson D, Senadeera S, Alamri Y, Fink J, Beharry J, Parsons MW, Levi C, Spratt N, Chew BLA, Hasnain MG, Miteff F, Rinkel L, Nio SS, Al-Hadethi S, Lim A, Coutinho J, Garcia-Esperon C, Wu TY, Berry-Noronha A.   +21 more
europepmc   +1 more source

Left Atrial Anomalous Band in Left Atrial Appendage

Internal Medicine
Nakajima, Yuki, Saito, Yuki, Hatta, Takumi, Okumura, Yasuo   +3 more
openaire   +2 more sources

Senolytics and exercise: Dual modalities for rejuvenating muscle

The Journal of Physiology, EarlyView.
Abstract figure legend The role of senolytics on the heart and skeletal muscle. Senescent cell burden increases with ageing, disuse and disease. The senolytics dasatinib+quercetin (D+Q), navitoclax and fisetin, as well as exercise, eliminate senescent cells, reducing senescent cell burden and their senescence‐associated secretory phenotype (SASP ...
Zeynep Elif Yesilyurt‐Dirican, Ce Qi, Uchenna Okpechi, Maya Strand Ford, Georgina M. Ellison‐Hughes   +4 more
wiley   +1 more source

Simultaneous Dual Left Atrial Appendage Occlusion Devices in a Single Setting-A Case Report. [PDF]

J Soc Cardiovasc Angiogr Interv
Mohiuddin A, Salih M, Assaf A, El-Kader AA, Hobbs W, Elkaialy A, Matar R, Al-Azizi K.   +7 more
europepmc   +1 more source

Electrophysiological characterization of pre‐adolescents born with intrauterine growth restriction: insights from clinical and computational data

The Journal of Physiology, EarlyView.
Abstract figure legend Depolarization and repolarization duration analysis was conducted in preadolescent groups with IUGR and controls using a 12‐lead ECG. Principal component analysis was applied over the 12‐lead ECGs to generate spatially transformed leads better suited for robust ECG fiducial points detection.
Freddy L. Bueno‐Palomeque, Ernesto Zacur, Esther Pueyo, Fàtima Crispi, Pablo Laguna, Ana Mincholé   +5 more
wiley   +1 more source

Left Atrial Appendage Thrombus in Hypertrophic Cardiomyopathy With Atrial Fibrillation-Common and Resistant to Treatment. [PDF]

J Am Heart Assoc
Massera D, Sherrid MV.
europepmc   +1 more source

Haemodynamic‐energetic mechanism of sudden cardiac death in severe aortic stenosis: A modelling study

The Journal of Physiology, EarlyView.
Abstract figure legend A sudden decrease in total peripheral resistance (TPR), as observed during vasovagal syncope, leads to a reduction in aortic systolic pressure (AO pressure) and afterload. In healthy individuals, the consequent decrease in left ventricular systolic pressure (LV pressure) lowers stroke work and myocardial energy expenditure.
Martin Dvoulety, Michal Sitina
wiley   +1 more source