Results 41 to 50 of about 7,583,455 (297)

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Postoperative 4-chamber cardiac function and outcomes following biatrial or left atrial Maze procedure for concomitant atrial fibrillationCentral MessagePerspective

JTCVS Open
Objectives: Effects of Maze procedure lesions on subsequent atrial/ventricular function, and clinical outcomes are not well delineated. We analyzed relationships among preoperative atrial strain, postoperative cardiac function, and clinical outcomes ...
Olga N. Kislitsina, MD, PhD, Patrick M. McCarthy, MD, Sukit Christopher Malaisrie, MD, Madeline Jankowski, BSN, Jane Kruse, BSN, Seokyung An, PhD, Abigail Baldridge, PhD, Kevin E. Hodges, MD, James D. Thomas, MD, Douglas R. Johnston, MD, James L. Cox, MD   +10 more
doaj   +1 more source

A Study on Left Atrial Function in Patients with Essential Hypertension Using Four-Dimensional Echocardiography [PDF]

Advanced Ultrasound in Diagnosis and Therapy
Objective Aimed to evaluate patients with essential hypertension (EH) using four-dimensional automatic left atrial quantification (4DLAQ) To assess the occurrence of EH.
Junrong Hong, MD, Pingyang Zhang, MD, PhD, Mengyao Fei, MD, Lingling Wang, MD
doaj   +1 more source

Assessment of Left Atrial Structure and Function by Echocardiography in Atrial Fibrillation

Diagnostics, 2022
Atrial fibrillation (AF) is the most common arrhythmia with significant morbidity and mortality. Exacerbated by the aging population, the prevalence of AF is gradually increasing. Accurate evaluation of structure and function of left atrium (LA) has important prognostic significance in patients with AF.
Mengmeng Ji, Lin He, Lang Gao, Yixia Lin, Mingxing Xie, Yuman Li   +5 more
openaire   +3 more sources

The inferior caval vein draining into the left atrial cavity : a rare case [PDF]

, 2011
The inferior vena cava (IVC) draining into the left atrium (LA) is exceedingly rare in the setting of the usual atrial arrangement (situs solitus).
Shiina, Y., Slavik, S., Yen Ho, S., Uemura, H., McCarthy, Karen   +4 more
core  

Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling

FEBS Open Bio, EarlyView.
Hydrogel‐based cardiac tissue models are advancing our understanding of heart health and disease. By incorporating electrical conductivity, aligned structures, and tunable mechanical properties, these platforms better replicate the complex environment of native heart tissue.
Harrison Porritt, Annika Winbo, Jenny Malmström   +2 more
wiley   +1 more source

LEFT ATRIAL FUNCTION: MODERN ASSESSMENT METHODS AND CLINICAL SIGNIFICANCE

Рациональная фармакотерапия в кардиологии, 2017
Assessment of the left atrial (LA) function is important aspect of comprehensive cardiovascular system estimation. Many cardiac diseases make an impact to LA work either by direct affect on myocardium or hemodynamic condition changing.
E. N. Pavlyukova, D. A. Kuzhel, G. V. Matyushin   +2 more
doaj   +1 more source

Acute Kidney Injury After Mechanical Thrombectomy for Stroke in Patients With Pre‐Existing Renal Impairment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Acute kidney injury (AKI) is a common but often underrecognized complication in ischemic stroke patients undergoing mechanical thrombectomy, particularly among those with pre‐existing renal impairment. This study evaluated the incidence, risk factors, and clinical impact of AKI in this high‐risk population.
Michał Borończyk, Marcel Pilarek, Emilia Jaworska, Natalia Kardas, Oliwia Barnaś, Julia Woźniak, Iga Machała, Julia Węgrzynek‐Gallina, Joanna Siuda, Anna Hawrot‐Kawecka, Anetta Lasek‐Bal   +10 more
wiley   +1 more source

Interaction of Intraprocedural Antiplatelets and Intravenous Thrombolysis in Acute Intracranial Stenting: RESISTANT Registry Subanalysis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction/Objective Acute intracranial stenting during endovascular thrombectomy (EVT) for ischemic stroke requires intraprocedural antiplatelet therapy (APT) to maintain patency. However, the hemorrhagic risk of combining APT with intravenous thrombolysis (IVT) remains uncertain.
Aaron Rodriguez‐Calienes, Leonardo Cruz‐Criollo, Eric Kontowicz, Marta Olivé‐Gadea, Francesco Diana, Johannes Kaesmacher, Adnan Mujanovic, Serdar Geyik, Songul Senadim, Amedeo Cervo, Andrea Salcuni, Mariangela Piano, Manuel Moreu, Alfonso López‐Frías, Ameer E. Hassan, Samantha Miller, Elena Zapata‐Arriaza, Asier de Albóniga‐Chindurza, Mauro Bergui, Stefano Molinaro, João André Sousa, Fábio Gomes, João Sargento‐Freitas, Andrea Alexandre, Alessandro Pedicelli, Jeremy Hofmeister, Paolo Machi, Luca Scarcia, Erwah Kalsoum, Jose Amorim, Torcato Meira, Leonardo Renieri, Francesco Capasso, Daniele Romano, Eduardo Bárcena‐Ruiz, David Seoane, Mohamad Abdalkader, Piers Klein, Thanh N. Nguyen, Catarina Perry da Câmara, Anderson Brito, Nashwa Abdelhakim, Isabel Fragata, Dileep R. Yavagal, Jude H. Charles, Jose Rodriguez Castro, Pedro Vega, Atilla Özcan Özdemir, Zehra Uysal Kocabaş, Stanislas Smajda, Sadiq Al Salman, Jane Khalife, Tudor G. Jovin, Francesco Biraschi, Francesca Richetti, Pedro Castro, Luis Albuquerque, Adnan Siddiqui, Vinay Jaikumar, Pedro Navia, Nikolaos Ntoulias, Marios Psychogios, Mariano Velo, Joaquín Zamarro, Gonzalo de Paco, Yazan Ashouri, Mohammad AlMajali, Juan F. Arenillas, Alicia Sierra, Michele Romoli, João Pedro Marto, Shadi Yaghi, Marc Ribo, Alejandro Tomasello, Manuel Requena, Santiago Ortega‐Gutierrez   +75 more
wiley   +1 more source

Early repolarization, left ventricular diastolic function, and left atrial size in professional soccer players

, 2010
Recent data have suggested a relation among long-term endurance sport practice, left atrial remodeling, and atrial fibrillation. We investigated the influence of an increased vagal tone, represented by the early repolarization (ER) pattern, on diastolic ...
Flachskampf, Frank,, Matthias Wilhelm, Frank Flachskampf, Hennig, Friedrich F, Christian Rost, Rost, Christian,, Klinghammer, Lutz,, Brem, Matthias,, Daniel, Werner G.,, Hennig, Friedrich,, Matthias H. Brem, Rost, Christian, Klinghammer, Lutz, Flachskampf, Frank, Friedrich F. Hennig, Wilhelm, Matthias,, Werner G. Daniel, Wilhelm, Matthias, Lutz Klinghammer, Brem, Matthias H, Daniel, Werner G, Brem MH, Daniel WG, Wilhelm M, Rost C, Hennig FF, Klinghammer L, Flachskampf F   +27 more
core   +1 more source