Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
The correlation between ultrasonographic morphology and structure of the left atrial appendage, blood flow velocity, and plasma galectin-3 levels with thrombus formation in the left atrial appendage of patients with atrial fibrillation [PDF]
Background: To explore the correlation between left atrial appendage morphology, blood flow velocity and plasma galectin-3 and thrombosis in patients with atrial fibrillation.
Zhao Linghui +8 more
doaj +1 more source
The inferior caval vein draining into the left atrial cavity : a rare case [PDF]
The inferior vena cava (IVC) draining into the left atrium (LA) is exceedingly rare in the setting of the usual atrial arrangement (situs solitus).
Shiina, Y. +4 more
core
Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling
Hydrogel‐based cardiac tissue models are advancing our understanding of heart health and disease. By incorporating electrical conductivity, aligned structures, and tunable mechanical properties, these platforms better replicate the complex environment of native heart tissue.
Harrison Porritt +2 more
wiley +1 more source
Left atrial size and contractile function in healthy dogs and dogs with chronic mitral valve disease
: In humans, left atrial enlargement and reduced contractile functions are associated with adverse cardiovascular events and a poor prognosis in many dilatation of the left atrium occurs with the gradual evolution of chronic mitral valve disease and is ...
Lilian C. Petrus +7 more
doaj +1 more source
Objective: To check of relation between blood pressure (BP) and arterial stiffness parameters and measures of left atrial volume to verify whether it is the arterial stiffness-related BP parameters or mean arterial pressure (MAP)that could be responsible
Marta Rojek +4 more
doaj +1 more source
Discrepancies in Identification of Left Atrial Enlargement Using Left Atrial Volume versus Left Atrial-to-Aortic Root Ratio in Dogs [PDF]
Abstract Background Left atrial size is prognostically important in dogs with myxomatous mitral valve disease (MMVD). Hypothesis/Objectives To compare the level of agreement in identification of left atrial ...
Wesselowski, S. +3 more
openaire +2 more sources
Estimated central blood volume in cirrhosis [PDF]
The estimated central blood volume (i.e., blood volume in the heart cavities, lungs and central arterial tree) was determined by multiplying cardiac output by circulatory mean transit time in 19 patients with cirrhosis and compared with sympathetic ...
Ring-Larsen, Helmer +5 more
core +1 more source
ABSTRACT Objectives Acute kidney injury (AKI) is a common but often underrecognized complication in ischemic stroke patients undergoing mechanical thrombectomy, particularly among those with pre‐existing renal impairment. This study evaluated the incidence, risk factors, and clinical impact of AKI in this high‐risk population.
Michał Borończyk +10 more
wiley +1 more source
A Study on Left Atrial Function in Patients with Essential Hypertension Using Four-Dimensional Echocardiography [PDF]
Objective Aimed to evaluate patients with essential hypertension (EH) using four-dimensional automatic left atrial quantification (4DLAQ) To assess the occurrence of EH.
Junrong Hong, MD, Pingyang Zhang, MD, PhD, Mengyao Fei, MD, Lingling Wang, MD
doaj +1 more source

