Results 261 to 270 of about 130,409 (304)
Fingerlike Mass in the Left Atrium
Lester Yarmush+3 more
openaire +3 more sources
A common issue in clinical drug development involves drug–drug interactions (DDI) that may lead to altered drug exposure and subsequent altered safety and efficacy of an investigational drug or concomitant medications (conmeds) in the target patient population.
Alice S. Tang+6 more
wiley +1 more source
What are double-outlet left atrium and double-outlet right atrium?
Richard Van Praagh
doaj
This study aimed to analyze differences in the exposure‐response relationship for factor Xa inhibitors (FXaI) between patients aged ≥ 80 and < 80 years. Patients with atrial fibrillation (AF) taking rivaroxaban, apixaban, or edoxaban were enrolled, and a single steady‐state trough concentration was measured.
Shin‐Yi Lin+7 more
wiley +1 more source
Navigating Pharmacogenomic Testing in Practice: Who to Test and When to Test
There is increasing attention on the clinical utility and value of pharmacogenetic (PGx) testing to individualize medication management. Most clinical practice guidelines from medical professional societies do not recommend routine PGx testing, with a few key exceptions.
James M. Stevenson+4 more
wiley +1 more source
ABSTRACT Angiosarcoma with malignant effusion is an uncommon yet clinically aggressive presentation, which poses as a diagnostic pitfall with its overlapping cytomorphologic features with metastatic adenocarcinoma. In this article, two cases reported in the literature were reviewed for cytology, immunocytochemistry, and clinical course.
Jamie C. Y. Lam+3 more
wiley +1 more source
Abstract Background While heart function is broadly conserved across vertebrates, the cellular phenotype of muscle cells (cardiomyocytes) varies across taxa and throughout ontogeny. Emerging evidence suggests that some attributes may correlate with the capacity for spontaneous cardiomyocyte replacement following injury.
Kathy Jacyniak+4 more
wiley +1 more source
Lineage labeling with zebrafish hand2 Cre and CreERT2 recombinase CRISPR knock‐ins
Abstract Background The ability to generate endogenous Cre recombinase drivers using CRISPR‐Cas9 knock‐in technology allows lineage tracing, cell type‐specific gene studies, and in vivo validation of inferred developmental trajectories from phenotypic and gene expression analyses. This report describes endogenous zebrafish hand2 Cre and CreERT2 drivers
Zhitao Ming+14 more
wiley +1 more source
Autopsy findings in cases of fatal COVID‐19 vaccine‐induced myocarditis
Abstract COVID‐19 vaccines have been linked to myocarditis, which, in some circumstances, can be fatal. This systematic review aims to investigate potential causal links between COVID‐19 vaccines and death from myocarditis using post‐mortem analysis.
Nicolas Hulscher+3 more
wiley +1 more source