Results 41 to 50 of about 2,090,027 (300)

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Left atrium and appendage changes following myocardial infarction.

open access: yes, 2015
LA maximum area in normal (A) and 4-weeks ischemic mice (B). LAA long axis in normal (C) and ischemic mice (D).
Elena Nobili (314243)   +6 more
core   +1 more source

Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling

open access: yesFEBS Open Bio, EarlyView.
Hydrogel‐based cardiac tissue models are advancing our understanding of heart health and disease. By incorporating electrical conductivity, aligned structures, and tunable mechanical properties, these platforms better replicate the complex environment of native heart tissue.
Harrison Porritt   +2 more
wiley   +1 more source

Left ventricular outflow tract to left atrium fistula as a complication of aortic root repair

open access: yesIHJ Cardiovascular Case Reports, 2023
A fistula between the left ventricular outflow tract and left atrium is a very rare phenomenon. In this case report, we will introduce a Marfan patient who underwent an aortic root repair, leading to a complication of a left ventricular outflow tract to ...
John S. Dayco   +5 more
doaj   +1 more source

Irreversible left atrium dilatation preceding left ventricular dysfunction during trastuzumab therapy

open access: yes, 2018
Irreversible left atrium dilatation preceding left ventricular dysfunction during trastuzumab ...
Ribichini, Flavio   +7 more
core   +1 more source

Acute Kidney Injury After Mechanical Thrombectomy for Stroke in Patients With Pre‐Existing Renal Impairment

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Acute kidney injury (AKI) is a common but often underrecognized complication in ischemic stroke patients undergoing mechanical thrombectomy, particularly among those with pre‐existing renal impairment. This study evaluated the incidence, risk factors, and clinical impact of AKI in this high‐risk population.
Michał Borończyk   +10 more
wiley   +1 more source

Spontaneous dissecting aneurysm of the left atrium complicated by cerebral embolism: A report of two cases with review of literature

open access: yesIndian Heart Journal, 2016
Left atrial dissection is a very uncommon complication of cardiac surgery and usually causes significant hemodynamic compromise. Little is known about spontaneous dissection of the left atrium.
Jagdish C. Mohan   +3 more
doaj   +1 more source

Left atrium: volumes, anatomy and function.

open access: yes, 2015
MLD: medio-lateral diameter, SID: supero-inferior diameter. Values are mean±SD.Left atrium: volumes, anatomy and function.
Elena Nobili (314243)   +6 more
core   +1 more source

Interaction of Intraprocedural Antiplatelets and Intravenous Thrombolysis in Acute Intracranial Stenting: RESISTANT Registry Subanalysis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction/Objective Acute intracranial stenting during endovascular thrombectomy (EVT) for ischemic stroke requires intraprocedural antiplatelet therapy (APT) to maintain patency. However, the hemorrhagic risk of combining APT with intravenous thrombolysis (IVT) remains uncertain.
Aaron Rodriguez‐Calienes   +75 more
wiley   +1 more source

Variations in the Pulmonary Venous Ostia of the Left Atrium: A Cross-sectional Study [PDF]

open access: yesJournal of Clinical and Diagnostic Research
Introduction: The left atrium typically receives the terminations of two pulmonary veins from each lung. The pulmonary veins are an important source of ectopic beats, initiating frequent paroxysms of atrial fibrillation. There is a paucity of data on the
GL Jyothi Lakshmi   +2 more
doaj   +1 more source

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