Results 41 to 50 of about 7,126 (236)

Cardiac Resynchronisation with Conduction System Pacing

Arrhythmia & Electrophysiology Review, 2023
To date, biventricular pacing (BiVP) has been the standard pacing modality for cardiac resynchronisation therapy. However, it is non-physiological, with the activation spreading between the left ventricular epicardium and right ventricular endocardium ...
Fatima M Ezzeddine, Isaac G Leon, Yong-Mei Cha   +2 more
doaj   +1 more source

Synchronization‐Dissipation in the Cardiorespiratory System

Advanced Science, EarlyView.
By modeling central nervous coupling and viscoelastic interactions in the cardiorespiratory system we show that synchronization produces a 10% gain in cardiac efficiency in humans. It is surmised that respiratory sinus arrhythmia improves cardiac pumping efficiency by reducing dynamic stress and power dissipation in the pulmonary vasculature.
Joshua R. Border, Alain Nogaret, Andrew Lefevre, Vishal Jain   +3 more
wiley   +1 more source

Echocardiographic response from Left Bundle Branch Area Pacing Optimized Cardiac Resynchronization Therapy (LOT-CRT) versus traditional CRT.

Heart Rhythm
BACKGROUND Traditional cardiac resynchronization therapy (CRT) with biventricular pacing (BVP) may be less effective in patients with nonspecific intraventricular conduction delay (NIVCD).
Gaurav A. Upadhyay, M. Jastrzębski, P. Foley, B. Chandrasekaran, Z. Whinnett, R. Schaller, R. Gardas, T. Richardson, P. Moskal, D. Kudlik, R. Stadler, P. Zimmerman, J. Burrell, R. Waxman, Richard N. Cornelussen, J. Lyne, B. Herweg, P. Vijayaraman   +17 more
semanticscholar   +1 more source

Multidimensional and Multifunctional Laser‐Induced Graphene (LIG) for Point‐of‐Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine

Advanced Science, EarlyView.
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang, Yurou Yuan, Xiaohong Ding, Wing Cheung Mak   +3 more
wiley   +1 more source

Efficacy and safety of left bundle branch pacing compared with left ventricular septal pacing: A systematic review and meta-analysis

Heart Rhythm O2
Background: Although numerous studies have compared the efficacy and safety of left bundle branch pacing (LBBP) and left ventricular (LV) septal pacing (LVSP), the results remain inconclusive. Objective: This meta-analysis aimed to systematically compare
Iwan Cahyo Santosa Putra, MD, Raymond Pranata, MD, Mohammad Iqbal, MD, PhD, FHRS, Giky Karwiky, MD, Chaerul Achmad, MD, PhD   +4 more
doaj   +1 more source

Discovery and Engineering of a Rat Endogenous Retrovirus Reverse Transcriptase for Efficient Prime Editing

Advanced Science, EarlyView.
We screened 558 reverse transcriptases and engineered an optimized rat endogenous retrovirus‐derived variant, enRERV‐RT, via structure‐guided engineering and deep mutational scanning. This enhanced prime editor, based on the engineered RT, outperforms conventional M‐MLV‐RT systems across plant and animal cells, particularly at hard‐to‐edit loci ...
Linsha Ma, Pengcheng Yao, Shengqi Wu, Yuanyuan Shi, Lang Qin, Baitao Li, Jiayi Zhu, Minhua Huang, Yichong Zhu, Yuwen Song, Jinhuan Pang, Ziping Guo, Guochuan Wu, Chen Wang, Kewei Xu, Ruihua Huang, Quan Kuang, Liang Qu, Changtian Pan, Xianrong Xie, Qinlong Zhu, Jiaying Huang, Qiupeng Lin   +22 more
wiley   +1 more source

Right-sided approach to left bundle branch area pacing combined with atrioventricular node ablation in a patient with persistent left superior vena cava and left bundle branch block: a case report

BMC Cardiovascular Disorders, 2022
Background Left bundle branch area pacing (LBBAP) is an alternative to right ventricular (RV) and biventricular (BiV) pacing in patients scheduled for pace and ablate treatment strategy.
Tine Prolič Kalinšek, David Žižek
doaj   +1 more source

Performance of an Active Fixation Stylet-Driven Lead in Left Bundle Branch Area Pacing: Results from INSIGHT-LBBA.

Heart Rhythm
BACKGROUND Left bundle branch area pacing (LBBAP) has been rapidly adopted despite a lack of leads with approved indications for LBBAP. OBJECTIVE To study the performance of a 6Fr active fixation, stylet-driven lead in LBBAP.
Daniel J. Friedman, I. Shadrin, S. Goldbarg, K. Trulock, Apoor Patel, Z. Loring, Sara A Coles, Gaurang D Gandhi, Gaurav A. Upadhyay, Nicholas Wold, Paul W. Jones, Stephen B. Ruble, Jonathan Weinstock, Christopher A. Latanich   +13 more
semanticscholar   +1 more source

Structural Polymorphism of polyG Inclusions Revealed by In Situ Cryo‐Electron Tomography

Advanced Science, EarlyView.
Correlative cryo‐electron tomography in primary cortical neurons and NIID mouse brain tissue reveals that polyG inclusions are interconnected ribbon‐like assemblies rather than canonical amyloid fibrils. Multiple compartment‐specific ribbon states show distinct 26S proteasome accessibility, while cytoplasmic ribbons contact and deform ER‐like ...
Yunwen Qian, Yalan Wan, Chen Chen, Xiaoyu Zheng, Wenjing Du, Junhan Yang, Zhihao Quan, Biyu Yang, Jiaxi Yu, Jie Zheng, Zhaoxia Wang, Jianwen Deng, Qiang Guo   +12 more
wiley   +1 more source

Case Report: Left bundle branch area pacing in cardiac resynchronization therapy increases conduction velocity

Frontiers in Cardiovascular Medicine
Several studies have suggested that the application of left bundle branch area pacing (LBBAP) in cardiac resynchronization therapy (CRT) holds promise as a treatment modality for correcting left bundle branch block (LBBB) while concurrently enhancing ...
Wenchang Zhang, Leyi Wang, Changjian He, Chunhua Ding   +3 more
doaj   +1 more source