Results 131 to 140 of about 222,137 (302)
Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.The top‐performing lipid nanoparticle, incorporating a novel ionizable lipid derived from vitamin B5, demonstrates high mRNA transfection efficiency, low toxicity, favorable stability, targeted delivery to lymphoid tissues, and high immunogenicity, showing promise as a carrier for mRNA vaccines for infectious diseases and cancer.
Soyeon Yoo +11 more
wiley +1 more source
Taut foliations in branched cyclic covers and left-orderable groups [PDF]
arXiv, 2017 We study the left-orderability of the fundamental groups of cyclic branched covers of links which admit co-oriented taut foliations. In particular we do this for cyclic branched covers of fibred knots in integer homology $3$-spheres and cyclic branched covers of closed braids.
arxiv
Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy
Advanced Healthcare Materials, EarlyView.The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq +4 more
wiley +1 more source
Multi-Feature Fusion and Compressed Bi-LSTM for Memory-Efficient Heartbeat Classification on Wearable Devices [PDF]
arXivIn this article, we present a resource-efficient approach for electrocardiogram (ECG) based heartbeat classification using multi-feature fusion and bidirectional long short-term memory (Bi-LSTM). The dataset comprises five original classes from the MIT-BIH Arrhythmia Database: Normal (N), Left Bundle Branch Block (LBBB), Right Bundle Branch Block (RBBB)
arxiv
Silicon Nanowire Mats Enable Advanced Bioelectrical Recordings in Primary DRG Cell Cultures
Advanced Healthcare Materials, EarlyView.SiNW mat‐based MEA (NW_MEA) enables continuous intracellular recordings from neurons in primary rat DRG cell cultures, identifying C‐fiber nociceptors. Supported by an astrocyte feeder layer, SiNW mat promotes DRG neuron and glial cell growth, preserving in vivo‐like cell characteristics and allowing drug‐modulated activity monitoring.
Ivano Lucarini +12 more
wiley +1 more source
ArrhythmiaVision: Resource-Conscious Deep Learning Models with Visual Explanations for ECG Arrhythmia Classification [PDF]
arXivCardiac arrhythmias are a leading cause of life-threatening cardiac events, highlighting the urgent need for accurate and timely detection. Electrocardiography (ECG) remains the clinical gold standard for arrhythmia diagnosis; however, manual interpretation is time-consuming, dependent on clinical expertise, and prone to human error.
arxiv
Simulated 2:1 Left Bundle-Branch Block [PDF]
, 1962 L Schamroth, Elliot Chesler
openalex +1 more source
Dendrimer Conjugates with PD‐L1‐Binding Peptides Enhance In Vivo Antitumor Immune Response
Advanced Healthcare Materials, EarlyView.In this paper, a novel nanoparticle scaffold composed of dendrimers conjugated with peptide‐based immune checkpoint inhibitors, enhancing drug delivery efficacy is introduced. By conjugating PD‐L1‐binding peptides to dendrimers, multivalent binding effects are harnessed, resulting in enhanced binding affinity, prolonged half‐life, and improved ...
DaWon Kim +11 more
wiley +1 more source
PATHOGENESIS OF LEFT BUNDLE BRANCH BLOCK [PDF]
Heart, 1948 Hakon Rasmussen, Torjus Moe
openaire +3 more sources