Results 211 to 220 of about 42,692 (298)

Characteristics of Cardiomyopathy in Patients With Chronic Left Bundle Branch Block Undergoing Right Ventricular Pacing. [PDF]

Pacing Clin Electrophysiol
Abe TA, Markson F, Friedman DJ, Jackson LR.   +3 more
europepmc   +1 more source

Targeting METTL3 Attenuates Thyroid Inflammatory Injury by Restoring Th17/Treg Balance through a YTHDC2‐m6A‐Dependent KDR/VEGFA Loop

Advanced Science, EarlyView.
METTL3‐mediated m6A modification stabilizes KDR/Kdr mRNA through YTHDC2, amplifying the VEGFA‐KDR feedback loop and disturbing Th17/Treg balance. This pathway promotes persistent inflammation and tissue damage in patients with AIT, and inhibiting the METTL3‐KDR axis effectively disrupts this circuit, alleviating thyroid tissue injury and disease ...
Qingyi Hu, Huan Liu, Anwen Ren, Zimei Tang, Jie Tan, Wen Yang, Jie Ming, Tao Huang   +7 more
wiley   +1 more source

Triage of Stable Patients With Suspected Acute Myocardial Infarction and Left Bundle Branch Block: A Multicenter, Propensity Score-Matched Analysis. [PDF]

Dtsch Arztebl Int
Macherey-Meyer S, Heyne S, Meertens MM, Finke K, Mauri V, Terporten J, Ahrens I, Baer FM, Eberhardt F, Horlitz M, Sinning JM, Meissner A, Rosswinkel B, Baldus S, Adler C, Lee S, KIM e.V..   +16 more
europepmc   +1 more source

Large‐Scale Genomics Reveals Three‐Source Ancestry and Layered Adaptation to High Altitude in Tibetan Chickens

Advanced Science, EarlyView.
Whole‐genome analysis of 1,054 chickens reveals three ancestral sources (NWC, SYA, and SHF) with distinct temporal entry patterns into the Tibetan Plateau. Route‐specific selection scans, calibrated against a demographic null, suggest complementary functional enrichments—vascular homeostasis (NWC), calcium signaling and cardiac adaptation (SYA), and ...
Zongyi Zhao, Ruixue Nie, Hailu Fan, Tenzin Ngodroup, Li Zhu, Hongbin Pan, Bo Zhang, Hao Zhang   +7 more
wiley   +1 more source

Left Bundle Branch Block as a Risk Factor for Heart Failure.

JAMA Netw Open
Thein AS, Dixit S, Soliman EZ, Heckbert SR, Psaty BM, Gottdiener J, Marcus GM.   +6 more
europepmc   +1 more source

Peak QRS/T ratio and the spatial ventricular gradient differentiate acute vs chronic left bundle branch block after transcatheter aortic valve replacement. [PDF]

Heart Rhythm O2
Waks JW, Poulin MF, Tung P, Stabenau HF, Haouzi A, Clarke JD, Zimetbaum P, d'Avila A, Ultimo B, Guibone KA, Kiernan K, Medline A, Peters NS, Sau A, Ng FS, Kramer DB, Shvilkin A, Laham RJ, Buxton AE.   +18 more
europepmc   +1 more source

Astrocytic Phenotypic Switching in Posterior Piriform Cortex Orchestrates Bone Cancer Pain–Depression Comorbidity via Purinergic–Noradrenergic Signaling

Advanced Science, EarlyView.
Bone cancer pain and depression share a common origin: astrocytic A2‐to‐A1 transition in the posterior piriform cortex. This phenotypic shift disrupts the ATP–adenosine–A2AR–norepinephrine axis, simultaneously driving nociceptive and affective dysfunction.
Jiang‐Ping Liu, Jun‐Han Zhang, Zhi‐Xuan Tan, Wei‐Bing Yan, Ya‐Ru Yuan, Yao Liu, Bing‐Di Wei, Meng‐Qi Ding, Zhuo‐Min Fu, Ying Liu, An‐Qi Wang, Lin Ma, Yong‐Hong Li, Er‐Qing Chai, Chao‐Jun Wei   +14 more
wiley   +1 more source

Restoration of Cardiac Function in Left Bundle Branch Block-Induced Cardiomyopathy via Conduction System Pacing: A Case Report. [PDF]

Am J Case Rep
Wang J, Han B, Wang X, Chen Z, Li W.
europepmc   +1 more source

The Trichinella Super‐Pangenome Reveals the Evolution of Encapsulation and Predicted Host–Parasite Protein Interactions

Advanced Science, EarlyView.
ABSTRACT The muscle capsule of Trichinella is a critical structure that impedes immune attacks and drug penetration, yet the molecular mechanisms underlying its formation remain poorly understood. Using a high‐quality super‐pangenome comprising 12 Trichinella species, we compared extensive genomic variations between encapsulating and non‐encapsulating ...
Qingbo Lv, Yi Liu, Ning Xu, Xiao Zhang, Yaming Yang, Chengyao Li, Hanhai Mao, Mingyuan Liu, Xiaolei Liu   +8 more
wiley   +1 more source

Left bundle branch block morphology on electrocardiogram after massive diphenhydramine overdose. [PDF]

Toxicol Rep
Yeung K, Moriguchi R, Hardin J, Galust H, Ghobrial M, Krause M, Seltzer J, Clark R.   +7 more
europepmc   +1 more source