Results 61 to 70 of about 139,184 (398)

Programming Cardiac Resynchronization Therapy for Electrical Synchrony: Reaching Beyond Left Bundle Branch Block and Left Ventricular Activation Delay

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2018
Background QRS narrowing following cardiac resynchronization therapy with biventricular (BiV) or left ventricular (LV) pacing is likely affected by patient‐specific conduction characteristics (PR, qLV, LV‐paced propagation interval), making a universal ...
N. Varma, D. O'Donnell, M. Bassiouny, P. Ritter, C. Pappone, J. Mangual, Daniel J. Cantillon, N. Badie, B. Thibault, Brian Wisnoskey   +9 more
semanticscholar   +1 more source

The role of fibroblast growth factors in cell and cancer metabolism

FEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

Left Bundle Branch Block Chest Pain Conundrum

Case Reports in Cardiology, 2020
Left bundle branch block is a pattern of altered ventricular depolarization and subsequently affects repolarization. These obscure patterns can affect the traditional ST segment shift criteria for the electrocardiographic detection of coronary ...
Karthik Seetharam, Ayesha Cheema, Gary Friedman, Roman Pachulski   +3 more
doaj   +1 more source

Bundle Branch Reentrant Ventricular Tachycardia [PDF]

, 2005
Bundle branch reentrant (BBR) tachycardia is an uncommon form of ventricular tachycardia (VT) incorporating both bundle branches into the reentry circuit.
Kusniec, Jairo, Mazur, Alexander, Strasberg, Boris   +2 more
core   +2 more sources

Brief remission of cardiac conduction defect under anaesthesia during trans-sphenoidal pituitary surgery [PDF]

, 2023
Acromegaly can cause paroxysmal arrhythmia and bundle branch blocks, which may or may not be symptomatic. Physiological stress induced by anaesthesia can exacerbate cardiac problems; nevertheless, reversal of such problems can also occur despite being ...
Kaur, Kirandeep, Kaur, Manpreet, Mahajan, Shalvi   +2 more
core   +2 more sources

Diagnosis of acute myocardial infarction in the presence of left bundle branch block

Heart, 2019
Objective Patients with suspected acute myocardial infarction (AMI) in the setting of left bundle branch block (LBBB) present an important diagnostic and therapeutic challenge to the clinician.
T. Nestelberger, L. Cullen, B. Lindahl, T. Reichlin, J. Greenslade, E. Giannitsis, M. Christ, B. Morawiec, Ò. Miró, F. Martín-Sánchez, D. Wussler, L. Koechlin, R. Twerenbold, W. Parsonage, J. Boeddinghaus, M. Rubini Giménez, C. Puelacher, K. Wildi, Tobias Buerge, P. Badertscher, Jeanne M. Du-Fay-de-Lavallaz, I. Strebel, Lukas Croton, Garnet Bendig, S. Osswald, J. Pickering, M. Than, C. Mueller   +27 more
semanticscholar   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Clinical outcomes of left bundle branch pacing compared to right ventricular apical pacing in patients with atrioventricular block

Clinical Cardiology, 2021
Left bundle branch pacing (LBBP) can produce near normalization of QRS duration. This has recently emerged as alternative technique to right ventricular pacing and His bundle pacing.
Shigeng Zhang, Jun-fang Guo, Aibin Tao, Baowei Zhang, Z. Bao, Guohui Zhang   +5 more
semanticscholar   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Prevalence of Bundle Branch Block and Axis Deviation in Permanent Atrial Fibrillation and Gender Differences

Annals of Noninvasive Electrocardiology
Objective To investigate two conditions that have been poorly investigated in the medical literature before in the context of atrial fibrillation: the coexistence and association of right or left bundle branch block and axis deviation in patients with ...
Raymond Farah, Mor Kdoshim, Rola Khamisy‐Farah   +2 more
doaj   +1 more source