Results 61 to 70 of about 222,137 (302)

KRAS and GNAS mutations in cell‐free DNA and in circulating epithelial cells in patients with intraductal papillary mucinous neoplasms—an observational pilot study

Molecular Oncology, EarlyView.
This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke, Marie Tölle, Philipp Walter, Kira Meißner, Mara Goetz, Jolanthe Kropidlowski, Andreas W. Berger, Jakob R. Izbicki, Felix Nickel, Thilo Hackert, Klaus Pantel, Harriet Wikman, Faik G. Uzunoglu   +12 more
wiley   +1 more source

Bundle Branch Reentrant Ventricular Tachycardia [PDF]

, 2005
Bundle branch reentrant (BBR) tachycardia is an uncommon form of ventricular tachycardia (VT) incorporating both bundle branches into the reentry circuit.
Kusniec, Jairo, Mazur, Alexander, Strasberg, Boris   +2 more
core   +2 more sources

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source

Prognosis of incidental left bundle branch block

EP Europace, 2020
Abstract Aims Incidental left bundle branch block (iLBBB) is a frequent cause for cardiology referrals. In such instances, there is uncertainty as to its prognosis. We sought to determine the utility of cardiovascular magnetic resonance (CMR) in the risk stratification of patients with iLBBB.
Francisco Leyva, Ben Holloway, Howard Marshall, Ayman Jani, Berthold Stegemann, Lucy Hudsmith, Richard Steeds, Joseph de Bono, Osita Okafor, Abbasin Zegard   +9 more
openaire   +3 more sources

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

FEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui, Silin Tu, Haibo Li, Zhancheng Zeng, Ruiqi Xiao, Jing Guo, Xiaoqi Liang, Chang Liu, Lijie Pan, Wenjie Chen, Mian Ge, Xiaofen Zhong, Linsen Ye, Huaxin Chen, Qi Zhang, Yan Xu   +15 more
wiley   +1 more source

Blokade Cabang Berkas Kiri (Left Bundle Branch Block) pada Miokarditis Difteri [PDF]

, 1993
Left bundle branch block in diphtheritic myocarditis A case study Left bundle branch block is very rare in children. A boy, 5 years old with diphtheritic myocarditis had left bundle branch block in ECG pattern during the first days in hospital.
A. Samik Wahab
core   +1 more source

“Crochetage” (Notch) on R wave in inferior limb leads: A new independent electrocardiographic sign of atrial septal defect [PDF]

, 1996
Objectives. This study sought to determine the clinical significance of a “crochetage” pattern—a notch near the apex of the R wave in electrocardiographic (ECG) inferior limb leads—in secundum atrial septal defect.Background.
Besse, Bruno, Desnos, Michel, Guerot, Claude, Hagège, Albert A., Heller, Joseph, Marie, François-Noël   +5 more
core   +1 more source

Painful Left Bundle Branch Block Syndrome Successfully Treated With Left Bundle Branch Area Pacing

JACC: Case Reports, 2020
Chest pain may be rarely associated with left bundle branch block (LBBB)-mediated ventricular dys-synchrony has been reported. This article reports 2 such cases, where left bundle branch area pacing resulted in resolution of the LBBB and associated ...
Aatish Garg, MD, Vivak Master, MD, Kenneth A. Ellenbogen, MD, Santosh K. Padala, MD   +3 more
doaj  

Knockout of the mitoribosome rescue factors Ict1 or Mtrfr is viable in zebrafish but not mice: compensatory mechanisms underlying each factor's loss

FEBS Open Bio, EarlyView.
Mitochondria contain two mitoribosome rescue factors, ICT1 and MTRFR (C12orf65). ICT1 also functions as a mitoribosomal protein in mice and humans, and its loss is lethal. Although Mtrfr knockout mice could not be generated, knockout zebrafish lines for ict1 and mtrfr were established.
Nobukazu Nameki, Chika Tomisawa, Soichiro Hoshino, Hidehiko Shimizu, Masashi Abe, Sho Arai, Kanako Kuwasako, Naoki Asakawa, Yusuke Inoue, Takuro Horii, Izuho Hatada, Masakatsu Watanabe   +11 more
wiley   +1 more source

Significance of ventricular late potentials in non-ischaemic dilated cardiomyopathy [PDF]

, 2017
To assess the incidence and clinical significance of ventricular late potentials in non-ischaemic dilated cardiomyopathy, 51 consecutive (44 male, seven female, mean age 53± 11 years) patients with dilated cardiomyopathy were studied.
ADAMEC, R., DENEREAZ, D., ZIMMERMANN, M.
core