Results 211 to 220 of about 14,635 (256)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Concurrent Multi-Beam Digital Predistortion Using FFT Beamforming and Virtual Arrays. [PDF]

Sensors (Basel)
Langborn B, Fager C, Hou R, Eriksson T.
europepmc   +1 more source

On Jordan Left Derivations

On Jordan Left Derivations
openaire  

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

A Comparative Study of Regression Methods for Solving the Timepix Calibration Task. [PDF]

Sensors (Basel)
Broulím J, Prokop M, Nouzák L, Smrčka P.   +3 more
europepmc   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

Optimal Site of the Reference Electrode for Recording the Compound Muscle Action Potential of the Deltoid Muscle. [PDF]

Muscle Nerve
Hamada Y, Oishi C, Kanbayashi T, Chiba A, Kobayashi S, Sonoo M.   +5 more
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Forehead and In-Ear EEG Acquisition and Processing: Biomarker Analysis and Memory-Efficient Deep Learning Algorithm for Sleep Staging with Optimized Feature Dimensionality. [PDF]

Sensors (Basel)
De Fazio R, Yalçınkaya ŞE, Cascella I, Del-Valle-Soto C, De Vittorio M, Visconti P.   +5 more
europepmc   +1 more source

Mapping Local Dissipation and Entropy Production in Complex and Active Fluids. [PDF]

J Phys Chem Lett
Desgranges C, Delhommelle J.
europepmc   +1 more source