Results 151 to 160 of about 109,591 (256)

Phenotypic profiling of pristane‐induced mimicking human systemic lupus erythematosus in Macaca fascicularis

Animal Models and Experimental Medicine, EarlyView.
Pristane (5 mL/kg) induced a robust systemic lupus erythematosus (SLE)‐like phenotype in Macaca fascicularis, marked by elevated antinuclear antibody (ANA) levels and systemic clinical, hematological, and biochemical changes. This model closely reflects human SLE and provides a translational platform for disease studies and therapeutic evaluation ...
Jonny Jonny, Soetojo Wirjopranoto, Chairul A. Nidom, I Ketut Sudiana, Terawan A. Putranto, Elisa D. Pratiwi, Tiza W. Mawaddah, Astria N. Nidom, Reviany V. Nidom, Setyarina Indrasari, Irma Y. Rosytania, Hiqmah Y. Yana, Sanindita Kusumastuti   +12 more
wiley   +1 more source

Long-Term Renal Outcomes Following Left Renal Vein Ligation Versus Direct Splenorenal Shunt Ligation in Living Donor Liver Transplantation: A 10-Year Single-Center Study. [PDF]

Transpl Int
Kang WH, Moon DB, Hwang S, Kim KH, Ahn CS, Ha TY, Song GW, Jung DH, Park GC, Yoon YI, Na BG, Kim SH, Kim SM, Lee SG.   +13 more
europepmc   +1 more source

Stem cell–based therapies for type 1 diabetes: Progress in differentiation, clinical translation, and immune protection

Animal Models and Experimental Medicine, EarlyView.
Directed differentiation of pluripotent stem cells into functional pancreatic β cells have emerged as a promising strategy for the radical treatment of type 1 diabetes, with preclinical and early clinical evidence demonstrating reversal of hyperglycemia and insulin independence.
Zifan Li, Yu Kang, Yuyu Niu
wiley   +1 more source

Dilation of the left renal vein: an indicator of spontaneous splenorenal shunt in chronic liver disease patients. [PDF]

Br J Radiol
Durur Karakaya A, Sorkun M, Akyıldız M, Kanmaz T, Gürses B.   +4 more
europepmc   +1 more source

Humanized immune system animal models and their recent applications

Animal Models and Experimental Medicine, EarlyView.
In this review, we provide an updated and comprehensive overview of the current state of humanized immune system animal model research. We discuss the variety of techniques used to produce humanized mice with their respective strengths and weaknesses, and evaluate the advantages and limitations of these models, including issues with incomplete immune ...
Nicolas Skuli, Rudra B. Amin, A’ishah Bakayoko, Marisa Kruidenier, Sahara Aqui, Sarah J. Skuli, Terence P. Gade   +6 more
wiley   +1 more source

Double retro-aortic left renal vein-a rare anatomical variant. [PDF]

BMJ Case Rep
Mhalasakant Khaladkar S, Krishnani KS, Mohanan K, Jhala NA.   +3 more
europepmc   +1 more source

Animal models of idiopathic membranous nephropathy: Recent advances and future perspectives

Animal Models and Experimental Medicine, EarlyView.
This review focuses on the evolution of idiopathic membranous nephropathy (IMN) animal models from traditional approaches (Heymann nephritis, C‐BSA, APA) to antigen‐specific models (PLA2R, THSD7A), critically evaluating their advances and limitations in replicating human IMN pathology.
Qiuying Liu, Huixian Bian, Jianhua Liu, Lina Wu, Zhijie Zhang, Hongli Zhao, Xiaosong Qin   +6 more
wiley   +1 more source

Robotic-assisted left renal vein transposition with distal gonadal vein anastomosis: A novel technique for dual venous drainage in nutcracker syndrome. [PDF]

J Vasc Surg Venous Lymphat Disord
Xu J, Cheong SU, Deng G, Xu Z, Huang Z, Ye Y, Wang H, Liu W, Li X, Li J, Huang Q, Li T, Di J.   +12 more
europepmc   +1 more source

Recent advances in the construction of humanized animal models and applications in translational medicine

Animal Models and Experimental Medicine, EarlyView.
Substantial advances have been achieved in the development of humanized mouse models, which have proven highly valuable in evaluating cancer immunotherapies and elucidating the mechanisms of infectious diseases. There is now a growing shift in research toward larger animal models—such as pigs—that offer greater physiological similarity to humans ...
Yanan Lyu, Yong‐Guang Yang, Zheng Hu
wiley   +1 more source

[MSB-31] Treatment of Nutcracker Syndrome: Outcomes with Left Renal Vein Transposition and Stenting. [PDF]

Turk Gogus Kalp Damar Cerrahisi Derg
Sarikaya S, Hancer H, Karasu H, Kırali K.   +3 more
europepmc   +1 more source